Steroidogenic Isoenzymes in Human Hair and Their Potential Role in Androgenetic Alopecia

    January 2003 in “ Dermatology ”
    Rolf Hoffmann
    Studysummary This article provides an overview of recent discoveries about steroidogenic enzymes involved in androgenetic alopecia but reports no new clinical results.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 17

    1. 17α-Estradiol Induces Aromatase Activity in Intact Human Anagen Hair Follicles Ex Vivo Experimental Dermatology · 2002
    2. Androgenetic Alopecia: Analysis of Proliferation and Apoptosis Archives of Dermatology · 2002
    3. An Investigation of Apoptosis in Androgenetic Alopecia American Journal of Dermatopathology · 2002
    4. Steroid Sulfatase in the Human Hair Follicle Concentrates in the Dermal Papilla Journal of Investigative Dermatology · 2001
    5. Possible Mechanisms of Miniaturization During Androgenetic Alopecia or Pattern Hair Loss Journal of The American Academy of Dermatology · 2001
    6. Androgen Responsive Genes as They Affect Hair Growth PubMed · 2001
    7. Finasteride Is the Main Inhibitor of 5α-Reductase Activity in Microdissected Dermal Papillae of Human Hair Follicles Archives of Dermatological Research · 1999
    8. Androgen-Dependent Beard Dermal Papilla Cells Secrete Autocrine Growth Factors in Response to Testosterone Unlike Scalp Cells ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1998
    9. Protease Nexin-1 Is Expressed in Human Dermal Papilla Cells and Is Affected by Androgen Journal of dermatological science · 1998
    10. Different Levels of 5α-Reductase Type I and II, Aromatase, and Androgen Receptor in Hair Follicles of Women and Men with Androgenetic Alopecia Journal of Investigative Dermatology · 1997
    11. Inhibition of Hair Growth by Testosterone in the Presence of Dermal Papilla Cells from the Frontal Bald Scalp of the Postpubertal Stumptailed Macaque Endocrinology · 1997
    12. Message of Nexin 1, a Serine Protease Inhibitor, Accumulates in the Follicular Papilla During Anagen of the Hair Cycle Journal of Cell Science · 1995
    13. Mechanism of Action of Androgen in Hair Follicles Journal of dermatological science · 1994
    14. Steroid Chemistry and Hormone Controls During the Hair Follicle Cycle Annals of the New York Academy of Sciences · 1991
    15. In Vitro Effects of Testosterone, Dihydrotestosterone, and Estradiol on Cell Growth of Human Hair Bulb Papilla Cells and Hair Root Sheath Fibroblasts Acta Dermato Venereologica · 1990
    16. Substrate Specific Sulfatase Activity from Hair Follicles in Recessive X-Linked Ichthyosis Acta Dermato Venereologica · 1987
    17. Serum Elevation of Dehydroepiandrosterone Sulfate Associated with Male Pattern Baldness in Young Men Journal of the American Academy of Dermatology · 1987

    Related research 3

    1. Finasteride as a Treatment for Male Androgenetic Alopecia e-Jurnal Medika Udayana · 2013
    2. Steroidogenic Isoenzymes in Human Hair and Their Potential Role in Androgenetic Alopecia Dermatology · 2003
    3. Effect of Finasteride, a 5 Alpha-Reductase Inhibitor, on Serum Gonadotropins in Normal Men The Journal of Clinical Endocrinology and Metabolism · 1992