Inhibition of Hair Growth by Testosterone in the Presence of Dermal Papilla Cells from the Frontal Bald Scalp of the Postpubertal Stumptailed Macaque

    January 1997 in “ Endocrinology ”
    Noriko Obana, Chawnshang Chang, Hideo Uno
    Studysummary Testosterone was found to inhibit hair follicle epithelial cell proliferation in adult stumptailed macaques only when dermal papilla cells from bald scalps were present, and this effect was reversed by the antiandrogen RU 58841.
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    Research cited in this study 7

    1. The Effects of Finasteride on Hair Growth, Hair Cycle Stage, and Serum Testosterone and Dihydrotestosterone in Adult Male and Female Stumptail Macaques The Journal of Clinical Endocrinology and Metabolism · 1994
    2. RU 58841, A New Specific Topical Antiandrogen: A Candidate of Choice for the Treatment of Acne, Androgenetic Alopecia, and Hirsutism The Journal of Steroid Biochemistry and Molecular Biology · 1994
    3. Regulation of Hair Follicle Development: An In Vitro Model for Hair Follicle Invasion of Dermis and Associated Connective Tissue Remodeling Journal of Investigative Dermatology · 1993
    4. Soluble Factors From Human Hair Papilla Cells And Dermal Fibroblasts Dramatically Increase The Clonal Growth Of Outer Root Sheath Cells Archives of Dermatological Research · 1993
    5. Androgens and the Hair Follicle: Cultured Human Dermal Papilla Cells as a Model System PubMed · 1991
    6. Hair Follicles and Associated Glands as Androgen Targets Clinics in endocrinology and metabolism · 1986
    7. The In Vitro Properties of Dermal Papilla Cell Lines Established From Human Hair Follicles British Journal of Dermatology · 1986