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2 / 2 resultslearn RU58841
a potent but unapproved and potentially problematic topical anti-androgen
Research
5 / 530 results![RU 58841, a new specific topical antiandrogen: A candidate of choice for the treatment of acne, androgenetic alopecia and hirsutism](/images/research/22c72f57-74fc-4f8d-b13d-4cb48dc748c4/small/2025.jpg)
research RU 58841, a new specific topical antiandrogen: A candidate of choice for the treatment of acne, androgenetic alopecia and hirsutism
RU 58841 may treat acne, hair loss, and excessive hair growth.
research RU 58841-myristate–prodrug development for topical treatment of acne and androgenetic alopecia.
![Percutaneous absorption of a new antiandrogen included in liposomes or in solution](/images/research/5a03d9de-df1e-42a7-8978-9edf6a684bc3/small/12617.jpg)
research Percutaneous absorption of a new antiandrogen included in liposomes or in solution
Liposomes can make the antiandrogen RU 58841 more effective for skin application by reducing absorption, increasing skin retention, and targeting sebaceous structures.
![Synthesis and structure–activity studies of side-chain derivatized arylhydantoins for investigation as androgen receptor radioligands](/images/research/23e7ef98-3530-48ad-b40f-c12ba9d50087/small/12612.jpg)
research Synthesis and structure–activity studies of side-chain derivatized arylhydantoins for investigation as androgen receptor radioligands
The nature of the side chain in RU 58841 derivatives greatly affects its AR affinity, with the N-(iodopropenyl) derivative 13 showing the highest AR binding affinity, suggesting its potential for developing high-affinity radioiodinated AR radioligands.
![Preliminary pharmacokinetics and metabolism of novel non-steroidal antiandrogens in the rat: Relation of their systemic activity to the formation of a common metabolite](/images/research/22218529-687d-4a87-a0b2-67630088537b/small/12618.jpg)
research Preliminary pharmacokinetics and metabolism of novel non-steroidal antiandrogens in the rat: Relation of their systemic activity to the formation of a common metabolite
Two non-steroidal antiandrogens, RU 58841 and RU 56187, form a common metabolite at different rates, which may influence their effects; RU 56187 could be used for prostate cancer treatment and RU 58841 for acne treatment.
Community Join
5 / 1000+ resultscommunity RU-58841 Lung Disease Possibility | Chest pain, "heart issues", etc
Some users of RU-58841 report cardiovascular symptoms like heart palpitations and chest tightness, which may be linked to its metabolites causing lung disease. The safety of RU-58841 is uncertain due to lack of long-term data and concerns about product purity, especially from gray market sources.
community Ru-58841 or KX-826 (Pyrilutamide)?
Exploring potential treatments for hair loss, with the focus being on comparing RU58841 and Pyrilutamide. Finasteride, Dutasteride, oral Minoxidil, microneedling, topical Minoxidil, Biotin, Zinc, Vitamin D and Nizoral are also discussed as part of a treatment stack.
community RU 58841, Minox, and Dutasteride 3 times a week. Two months difference. 25 years old. After stopping RU I do believe I lost some of my gains. I think it’s too soon to really get the good effects of DUT.
User shared progress with RU 58841, Minox, and Dutasteride 3 times a week for hair loss. Others noticed improvements and expect great gains over the next year.
community RU-58841 Experience (15mg daily dissolved in stemoxydine)
User experienced reduced hair loss with 15mg RU in Serioxyl but had concerning chest pain. Others suggested consulting a doctor or lowering the dose.
community Ru 58841 and essential oils question
The user discusses using essential oils like peppermint, rosemary, tea tree, and lavender to improve hair thickness and seborrheic dermatitis. They plan to add RU58841 to their routine and seek advice on using it alongside the essential oils without interference.