An Appraisal of Laboratory Models of Androgenetic Alopecia: A Systematic Review

    March 2021 in “ Skin health and disease
    Sylvia Ntombifuthi. Ntshingila, Nonhlanhla P. Khumalo, M Engel, A. T. Arowolo
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    TLDR Better hair loss models needed for research.
    This document is a systematic review of laboratory models used to study androgenetic alopecia (AGA). The authors evaluated various animal and cell culture models used to study AGA and found that while each model had its strengths and limitations, none of them fully replicated the complex pathogenesis of AGA in humans. The authors suggest that future research should focus on developing more comprehensive models that incorporate multiple factors involved in AGA, such as genetics, hormonal regulation, and immune response.
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