Histological Assessment of Follicular Delivery of Flutamide by Solid Lipid Nanoparticles: Potential Tool for the Treatment of Androgenic Alopecia

    July 2015 in “ Drug Development and Industrial Pharmacy ”
    Hamed Hamishehkar, Saeed Ghanbarzadeh, Sasan Sepehran … Maryam Kouhsoltani
    Studysummary This study concluded that Flutamide-loaded solid lipid nanoparticles may enhance hair follicle drug delivery and promote hair growth in androgenic alopecia compared to a Flutamide hydroalcoholic solution.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on tandfonline.com →
    Discuss this study in the Community →

    Research cited in this study 14

    1. Comparison of Rheological Properties, Follicular Penetration, Drug Release, and Permeation Behavior of a Novel Topical Drug Delivery System and a Conventional Cream European journal of pharmaceutics and biopharmaceutics · 2014
    2. Development, Formulation, and Characterization of an Adapalene-Loaded Solid Lipid Microparticle Dispersion for Follicular Penetration International journal of pharmaceutics · 2014
    3. Influence of Massage and Occlusion on the Ex Vivo Skin Penetration of Rigid Liposomes and Invasomes European journal of pharmaceutics and biopharmaceutics · 2013
    4. Design and In Vitro Evaluation of Finasteride-Loaded Liquid Crystalline Nanoparticles for Topical Delivery Aaps Pharmscitech · 2012
    5. Penetration of Drugs Through Skin: A Complex Rate-Controlling Membrane 2012
    6. An Overview on 5α-Reductase Inhibitors Steroids · 2009
    7. Formulation and In Vitro Assessment of Minoxidil Niosomes for Enhanced Skin Delivery International Journal of Pharmaceutics · 2009
    8. Targeted Transfollicular Delivery of Artocarpin Extract from Artocarpus Incisus by Means of Microparticles European Journal of Pharmaceutics and Biopharmaceutics · 2007
    9. Enhancement of Follicular Delivery of Finasteride by Liposomes and Niosomes International Journal of Pharmaceutics · 2006
    10. New 5α-Reductase Inhibitors: In Vitro and In Vivo Effects Steroids · 2005
    11. Androgens and Alopecia Molecular and Cellular Endocrinology · 2002
    12. New Topical Antiandrogenic Formulations Can Stimulate Hair Growth in Human Bald Scalp Grafted Onto Mice International Journal of Pharmaceutics · 2000
    13. Comparison of Finasteride and Flutamide in the Treatment of Idiopathic Hirsutism Fertility and Sterility · 1999
    14. Treatment of Hirsutism with the Pure Antiandrogen Flutamide Journal of the American Academy of Dermatology · 1990