Androgens and Alopecia

    December 2002 in “ Molecular and Cellular Endocrinology ”
    Keith D. Kaufman
    Studysummary This study found that finasteride improves scalp hair growth in men with male pattern hair loss by reducing scalp dihydrotestosterone levels, but it did not benefit postmenopausal women with female pattern hair loss.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 19

    1. Journal Review: Long-Term (5-Year) Multinational Experience with Finasteride 1mg in the Treatment of Men with Androgenetic Alopecia Hair transplant forum international · 2002
    2. Female Pattern Hair Loss Journal of The American Academy of Dermatology · 2001
    3. Hair Disorders Primary Care · 2000
    4. Measuring Reversal of Hair Miniaturization in Androgenetic Alopecia by Follicular Counts in Horizontal Sections of Serial Scalp Biopsies: Results of Finasteride 1mg Treatment of Men and Postmenopausal Women Journal of Investigative Dermatology Symposium Proceedings · 1999
    5. Immunohistochemical Localization of Types 1 and 2 5α-Reductase in Human Scalp British Journal of Dermatology · 1999
    6. Finasteride in the Treatment of Men with Frontal Male Pattern Hair Loss Journal of The American Academy of Dermatology · 1999
    7. Finasteride Is the Main Inhibitor of 5α-Reductase Activity in Microdissected Dermal Papillae of Human Hair Follicles Archives of Dermatological Research · 1999
    8. Novel Agents for the Treatment of Alopecia Seminars in Cutaneous Medicine and Surgery · 1998
    9. Finasteride in the Treatment of Men with Androgenetic Alopecia Journal of The American Academy of Dermatology · 1998
    10. Androgen Metabolism as It Affects Hair Growth in Androgenetic Alopecia Dermatologic Clinics · 1996
    11. The Effects of Finasteride (Proscar) on Hair Growth, Hair Cycle Stage, and Serum Testosterone and Dihydrotestosterone in Adult Male and Female Stumptail Macaques (Macaca Arctoides) The Journal of Clinical Endocrinology and Metabolism · 1994
    12. The Effect of Finasteride, a 5 Alpha-Reductase Inhibitor, on Scalp Skin Testosterone and Dihydrotestosterone Concentrations in Patients With Male Pattern Baldness The Journal of Clinical Endocrinology and Metabolism · 1994
    13. A Prospective Study of the Prevalence of Clear-Cut Endocrine Disorders and Polycystic Ovaries in 350 Patients Presenting with Hirsutism or Androgenic Alopecia Clinical Endocrinology · 1994
    14. Comparison of Flutamide and Spironolactone in the Treatment of Hirsutism: A Randomized Controlled Trial Fertility and Sterility · 1994
    15. Diagnostic and Predictive Value of Horizontal Sections of Scalp Biopsy Specimens in Male Pattern Androgenetic Alopecia Journal of The American Academy of Dermatology · 1993
    16. Natural Progression of Male Pattern Baldness in Young Men Clinical and Experimental Dermatology · 1991
    17. The Comparative Histopathology of Male-Pattern Baldness and Senescent Baldness Clinics in Dermatology · 1988
    18. Patterned Androgenic Alopecia in Women Journal of The American Academy of Dermatology · 1988
    19. Testosterone Metabolism in the Skin: A Review of Its Function in Androgenetic Alopecia, Acne Vulgaris, and Idiopathic Hirsutism Including Recent Studies with Antiandrogens Archives of Dermatology · 1975

    Related research 9

    1. Pharmacological Therapeutics in Androgenetic Alopecia Journal of The Korean Medical Association · 2020
    2. Hair Loss (Alopecia or Baldness) 2018
    3. Finasteride in the Treatment of Female Androgenic Alopecia PharmaTutor · 2014
    4. Characteristics of Korean Scalp Hair and Male Pattern Baldness Journal of The Korean Medical Association · 2013
    5. Evaluation of Androgens in the Scalp Hair and Plasma of Patients with Male-Pattern Baldness Before and After Finasteride Administration British Journal of Dermatology · 2006
    6. Androgens and Alopecia Molecular and Cellular Endocrinology · 2002
    7. Finasteride in the Treatment of Men with Androgenetic Alopecia Journal of The American Academy of Dermatology · 1998
    8. Histopathological and Topical Immunological Changes in Alopecia Journal of the European Academy of Dermatology and Venereology · 1998
    9. The Effect of Finasteride, a 5 Alpha-Reductase Inhibitor, on Scalp Skin Testosterone and Dihydrotestosterone Concentrations in Patients with Male Pattern Baldness The Journal of Clinical Endocrinology and Metabolism · 1994