Pharmacological Therapeutics in Androgenetic Alopecia

    Young Ho Kim, Hyojin Park
    Studysummary This review discusses treatment options for androgenetic alopecia, with a focus on the better efficacy of oral finasteride and dutasteride over topical minoxidil for male pattern hair loss, but it reports no new clinical results.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 42

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    2. Prostaglandins in Androgenetic Alopecia in 12 Men and Four Women Journal of The European Academy of Dermatology and Venereology · 2019
    3. The Efficacy and Safety of Dutasteride Compared with Finasteride in Treating Men with Androgenetic Alopecia: A Systematic Review and Meta-Analysis Clinical Interventions in Aging · 2019
    4. The Efficacy and Use of Finasteride in Women: A Systematic Review International Journal of Dermatology · 2019
    5. Long-Term (10-Year) Efficacy of Finasteride in 523 Japanese Men with Androgenetic Alopecia Clinical research and trials · 2019
    6. Evaluation of Long-Term Efficacy of Finasteride in Korean Men with Androgenetic Alopecia Using the Basic and Specific Classification System Journal of Dermatology · 2018
    7. Adverse Sexual Effects of Treatment with Finasteride or Dutasteride for Male Androgenetic Alopecia: A Systematic Review and Meta-Analysis Acta dermato-venereologica · 2018
    8. Evidence-Based Guideline for the Treatment of Androgenetic Alopecia in Women and Men – Short Version Journal of The European Academy of Dermatology and Venereology · 2017
    9. The Effectiveness of Treatments for Androgenetic Alopecia: A Systematic Review and Meta-Analysis Journal of The American Academy of Dermatology · 2017
    10. Androgenetic Alopecia: A Review Endocrine · 2017
    11. Therapeutic Efficacy of a Combination Therapy of Topical 17α-Estradiol and Topical Minoxidil on Female Pattern Hair Loss: A Noncomparative, Retrospective Evaluation Annals of Dermatology · 2017
    12. Adverse Effects and Safety of 5-Alpha Reductase Inhibitors (Finasteride, Dutasteride): A Systematic Review PubMed · 2016
    13. A Novel Finasteride 0.25% Topical Solution for Androgenetic Alopecia: Pharmacokinetics and Effects on Plasma Androgen Levels in Healthy Male Volunteers International Journal of Clinical Pharmacology and Therapeutics · 2014
    14. A Randomized, Active- and Placebo-Controlled Study of the Efficacy and Safety of Different Doses of Dutasteride Versus Placebo and Finasteride in the Treatment of Male Subjects with Androgenetic Alopecia Journal of The American Academy of Dermatology · 2014
    15. Prostaglandin D2 Inhibits Wound-Induced Hair Follicle Neogenesis Through the Receptor Gpr44 Journal of Investigative Dermatology · 2012
    16. Guidelines for Management of Androgenetic Alopecia Based on BASP Classification: The Asian Consensus Committee Guideline Journal of The European Academy of Dermatology and Venereology · 2012
    17. Hair: What Is New in Diagnosis and Management? Dermatologic Clinics · 2012
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    19. Prostaglandin D2 Inhibits Hair Growth and Is Elevated in Bald Scalp of Men with Androgenetic Alopecia Science Translational Medicine · 2012
    20. Global Photographic Assessment of Men Aged 18 to 60 Years with Male Pattern Hair Loss Receiving Finasteride 1 mg or Placebo Journal of The American Academy of Dermatology · 2012
    21. The 5 Alpha-Reductase Isozyme Family: A Review of Basic Biology and Their Role in Human Diseases Advances in Urology · 2011
    22. Evidence-Based Guideline for the Treatment of Androgenetic Alopecia in Women and Men Journal der Deutschen Dermatologischen Gesellschaft · 2011
    23. A Randomized Double-Blind Placebo-Controlled Pilot Study to Assess the Efficacy of a 24-Week Topical Treatment by Latanoprost 0.1% on Hair Growth and Pigmentation in Healthy Volunteers with Androgenetic Alopecia Journal of The American Academy of Dermatology · 2011
    24. Finasteride, 1 Mg Daily Administration on Male Androgenetic Alopecia in Different Age Groups: 10-Year Follow-Up Dermatologic Therapy · 2011
    25. Novel Treatment of Female-Pattern Androgenetic Alopecia with Injected Bimatoprost 0.03% Solution PubMed · 2011
    26. A Randomized, Single-Blind Trial of 5% Minoxidil Foam Once Daily Versus 2% Minoxidil Solution Twice Daily in the Treatment of Androgenetic Alopecia in Women Journal of The American Academy of Dermatology · 2011
    27. S1 Guideline for Diagnostic Evaluation in Androgenetic Alopecia in Men, Women, and Adolescents British Journal of Dermatology · 2010
    28. Efficacy, Safety, and Tolerability of Dutasteride 0.5 mg Once Daily in Male Patients with Male Pattern Hair Loss: A Randomized, Double-Blind, Placebo-Controlled, Phase III Study Journal of The American Academy of Dermatology · 2010
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    30. Susceptibility Variants for Male-Pattern Baldness on Chromosome 20p11 Nature Genetics · 2008
    31. Medical Treatments for Male and Female Pattern Hair Loss Journal of The American Academy of Dermatology · 2008
    32. A Multicenter, Randomized, Placebo-Controlled, Double-Blind Clinical Trial of a Novel Formulation of 5% Minoxidil Topical Foam Versus Placebo in the Treatment of Androgenetic Alopecia in Men Journal of The American Academy of Dermatology · 2007
    33. A New Classification of Pattern Hair Loss That Is Universal for Men and Women: Basic and Specific (BASP) Classification Journal of The American Academy of Dermatology · 2007
    34. Genetic Variation in the Human Androgen Receptor Gene Is the Major Determinant of Common Early-Onset Androgenetic Alopecia American Journal of Human Genetics · 2005
    35. A Randomized, Placebo-Controlled Trial of 5% and 2% Topical Minoxidil Solutions in the Treatment of Female Pattern Hair Loss Journal of The American Academy of Dermatology · 2004
    36. Minoxidil: Mechanisms of Action on Hair Growth British Journal of Dermatology · 2004
    37. A Randomized Clinical Trial of 5% Topical Minoxidil Versus 2% Topical Minoxidil and Placebo in the Treatment of Androgenetic Alopecia in Men Journal of The American Academy of Dermatology · 2002
    38. Chronic Treatment with Finasteride Daily Does Not Affect Spermatogenesis or Semen Production in Young Men The Journal of Urology · 1999
    39. Immunohistochemical Localization of Types 1 and 2 5α-Reductase in Human Scalp British Journal of Dermatology · 1999
    40. Balding Hair Follicle Dermal Papilla Cells Contain Higher Levels of Androgen Receptors Than Those From Non-Balding Scalp Journal of Endocrinology · 1998
    41. Cultured Dermal Papilla Cells From Androgen-Dependent Human Hair Follicles Contain More Androgen Receptors Than Those From Non-Balding Areas Of Scalp Journal of Endocrinology/Journal of endocrinology · 1992
    42. Metabolism of Androgens by Isolated Human Beard Hair Follicles Steroids · 1971