Efficacy, Safety, and Tolerability of Dutasteride 0.5 mg Once Daily in Male Patients with Male Pattern Hair Loss: A Randomized, Double-Blind, Placebo-Controlled, Phase III Study

    June 2010 in “ Journal of The American Academy of Dermatology ”
    Hee Chul Eun, Oh Joon Kwon, Je Young Yeon, Hyo Soon Shin, Byung-Gee Kim, Byung In Ro, Han Ik Cho, Woo-Young Sim, Bark-Lynn Lew, Won Young Lee, Hwa Chun Park, Seung Bong Hong, Jae Hong Ji
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    TLDR Dutasteride 0.5 mg daily improves hair growth safely in men with hair loss.
    A study from 12 years ago evaluated the efficacy, safety, and tolerability of dutasteride 0.5 mg once daily in male patients with male pattern hair loss. The study found that dutasteride improved hair growth and was well tolerated, with no significant difference in adverse events between the dutasteride and placebo groups. The study concluded that dutasteride 0.5 mg once daily is an effective and safe treatment option for male patients with male pattern hair loss.
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      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  828 upvotes 5 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community I am a dermatologist with a clinical interest in alopecia. AMA

      in Will treatment work for me? 2 years ago
      In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.

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