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    Glossary Placebo-Controlled

    comparison involves an inactive substance to test treatment efficacy

    A placebo-controlled study is a type of clinical trial where one group of participants receives the experimental treatment, while another group receives a placebo—a substance with no therapeutic effect, often a sugar pill. This design helps researchers determine the actual effectiveness of the treatment by comparing outcomes between the treated group and the placebo group, thereby accounting for the placebo effect, where participants may experience perceived or actual improvements in their condition simply because they believe they are receiving treatment.

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    Research 10 of 1000+

    1. A randomized, placebo-controlled trial of 5% and 2% topical minoxidil solutions in the treatment of female pattern hair loss Journal of The American Academy of Dermatology · 2004 · 219 citations
    2. A placebo-controlled, double-blind crossover study of fluoxetine in trichotillomania American Journal of Psychiatry · 1991 · 180 citations
    3. Placebo-controlled oral pulse prednisolone therapy in alopecia areata Journal of the American Academy of Dermatology · 2005 · 141 citations
    4. Efficacy, safety, and tolerability of dutasteride 0.5 mg once daily in male patients with male pattern hair loss: A randomized, double-blind, placebo-controlled, phase III study Journal of The American Academy of Dermatology · 2010 · 92 citations
    5. A double-blind, placebo-controlled study of inositol in trichotillomania International clinical psychopharmacology · 2016 · 18 citations
    6. The German Double‐Blind Placebo‐Controlled Evaluation of Topical Minoxidil Solution in the Treatment of Early Male Pattern Baldness International Journal of Dermatology · 1988 · 17 citations
    7. Minoxidil 2% lotion for eyebrow enhancement: A randomized, double-blind, placebo-controlled, spilt-face comparative study The Journal of Dermatology · 2013 · 13 citations
    8. A randomized, placebo-controlled trial of 1% topical minoxidil solution in the treatment of androgenetic alopecia in Japanese women. PubMed · 2007 · 10 citations
    9. Intradermal injections with 0.5% minoxidil for the treatment of female androgenetic alopecia: A randomized, placebo‐controlled trial Dermatologic Therapy · 2020 · 7 citations
    10. Safety and efficacy of ALRV5XR in women with androgenetic alopecia or telogen effluvium: A randomised, double-blinded, placebo-controlled clinical trial EClinicalMedicine · 2021 · 6 citations
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    Community 10 of 62

    1. Korean Laser Helmet has a 44% increase in hair growth vs 0% growth in placebo in a double-blinded randomized controlled clinical trial. Reddit · 5 Oct 2025
    2. Pumkin Seed Oil 400mg/day oral, 6 month Randomized, Double-Blind, Placebo-Controlled Trial (N=76) Reddit · 21 Sept 2022
    3. Amplifica AMP-303 study results are expected late this summer Reddit · 19 Jul 2024
    4. Why don’t people just just DUT instead of FIN? Reddit · 22 Feb 2024
    5. Why hasn’t anybody or any company done experiments on whether minoxidil and finasteride have effects on human collagen and elastin after a year of use compared to placebo? (In vivo not vitro) Reddit · 4 Feb 2026
    6. RCT: Rosemary-lavender oil formulation shown to stimulate hair growth when compared to placebo (2025) Reddit · 31 Dec 2025
    7. Reason why placebo group got regrow on trial phase 3 Reddit · 27 Aug 2024
    8. The Placebo Group Has It Worse Than The Standard Prescription 0.5mg Group. -The fear is all in your head. Reddit · 29 Sept 2025
    9. Am I getting results or is this just a placebo? Reddit · 1 Sept 2025
    10. Any bludfluw or placebo supplements to slow down graying? Reddit · 14 May 2024
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    Learn 10 of 22

    1. HMI-115 Experimental antibody that blocks the prolactin receptor
    2. Alfatradiol Weak form of estrogen applied to the scalp
    3. Latanoprost Prostaglandin eye drop used for glaucoma
    4. Follistatin Protein that blocks activin, a growth-regulating signal
    5. Melatonin Hormone that regulates sleep, sold as a supplement
    6. Hair Multiplication extract, clone, and reinsert your own hair cells
    7. Metformin Diabetes drug that lowers blood sugar
    8. Dexpanthenol Provitamin B5, a moisturiser in hair and skin products
    9. Finasteride Popular 5-alpha reductase inhibitor that lowers DHT, taken as a pill or used topically
    10. Neem Oil Oil from the neem tree, used in traditional remedies
    All learn results →