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    Glossary Placebo-Controlled

    comparison involves an inactive substance to test treatment efficacy

    A placebo-controlled study is a type of clinical trial where one group of participants receives the experimental treatment, while another group receives a placebo—a substance with no therapeutic effect, often a sugar pill. This design helps researchers determine the actual effectiveness of the treatment by comparing outcomes between the treated group and the placebo group, thereby accounting for the placebo effect, where participants may experience perceived or actual improvements in their condition simply because they believe they are receiving treatment.

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    Research 30 of 1000+

    1. A randomized, placebo-controlled trial of 5% and 2% topical minoxidil solutions in the treatment of female pattern hair loss Journal of The American Academy of Dermatology · 2004 · 219 citations
    2. A placebo-controlled, double-blind crossover study of fluoxetine in trichotillomania American Journal of Psychiatry · 1991 · 180 citations
    3. Placebo-controlled oral pulse prednisolone therapy in alopecia areata Journal of the American Academy of Dermatology · 2005 · 141 citations
    4. Efficacy, safety, and tolerability of dutasteride 0.5 mg once daily in male patients with male pattern hair loss: A randomized, double-blind, placebo-controlled, phase III study Journal of The American Academy of Dermatology · 2010 · 92 citations
    5. A double-blind, placebo-controlled study of inositol in trichotillomania International clinical psychopharmacology · 2016 · 18 citations
    6. The German Double‐Blind Placebo‐Controlled Evaluation of Topical Minoxidil Solution in the Treatment of Early Male Pattern Baldness International Journal of Dermatology · 1988 · 17 citations
    7. Minoxidil 2% lotion for eyebrow enhancement: A randomized, double-blind, placebo-controlled, spilt-face comparative study The Journal of Dermatology · 2013 · 13 citations
    8. A randomized, placebo-controlled trial of 1% topical minoxidil solution in the treatment of androgenetic alopecia in Japanese women. PubMed · 2007 · 10 citations
    9. Intradermal injections with 0.5% minoxidil for the treatment of female androgenetic alopecia: A randomized, placebo‐controlled trial Dermatologic Therapy · 2020 · 7 citations
    10. Safety and efficacy of ALRV5XR in women with androgenetic alopecia or telogen effluvium: A randomised, double-blinded, placebo-controlled clinical trial EClinicalMedicine · 2021 · 6 citations
    11. Sesquiterpene-Enriched Extract of <i>Curcuma aeruginosa</i> Roxb. Retards Axillary Hair Growth: A Randomised, Placebo-Controlled, Double-Blind Study Skin Pharmacology and Physiology · 2018 · 5 citations
    12. Efficacy and safety of Latilactobacillus curvatus LB-P9 on hair health: a randomized, double-blind, placebo-controlled clinical trial Frontiers in Nutrition · 2024 · 5 citations
    13. Placebo‐controlled dose‐effect studies with topical minoxidil 2% or 5% in male‐patterned hair loss treated with oral finasteride employing an analytical and exhaustive study protocol Skin Research and Technology · 2020 · 5 citations
    14. Hair growth effect of traditional Chinese medicine BeauTop on androgenetic alopecia patients: A randomized double-blind placebo-controlled clinical trial Experimental and Therapeutic Medicine · 2016 · 5 citations
    15. Intradermal Botulinum Toxin A Injection for Scalp Sebum Secretion Regulation: A Multicenter, Randomized, Double-Blinded, Placebo-Controlled, Prospective Study in Chinese Subjects Aesthetic Surgery Journal · 2022 · 4 citations
    16. The efficacy of subcutaneous slow‐release melatonin implants in the prevention of canine flank alopecia recurrence is uncertain: A double‐blind, randomized, placebo‐controlled study Veterinary Dermatology · 2022 · 3 citations
    17. Safety and efficacy of ALRV5XR in men with androgenetic alopecia: A randomised, double-blinded, placebo-controlled clinical trial EClinicalMedicine · 2021 · 3 citations
    18. A Randomized, Double-Blind, Placebo-Controlled Pilot Study to Evaluate the Efficacy and Safety of Latanoprost for Eyelash Growth in Aesthetic Medicine Cosmetics · 2023 · 2 citations
    19. Placebo controlled clinical evaluation of a topical moisturizer formula containing phytol Journal of The American Academy of Dermatology · 2017 · 1 citations
    20. Efficacy, Safety, and Tolerability of Upadacitinib in Adults and Adolescents With Severe Alopecia Areata: Results From the Randomized, Placebo-Controlled, Double-Blind Phase 3 Program (UP-AA) SKIN The Journal of Cutaneous Medicine · 2025
    21. 61720 The effect of sublingual minoxidil on androgenetic alopecia in transgender individuals receiving testosterone for gender-affirmation: A 24-week single-centre double-blinded, randomized, placebo-controlled clinical trial Journal of the American Academy of Dermatology · 2025
    22. Effects of Shampoo Containing Plantago asiatica L. on Hair Thickness, Density, and Shedding: A Double-Blind, Randomized, Placebo-Controlled Clinical Study Cosmetics · 2025
    23. Efficacy and Safety of Low-Molecular-Weight Collagen Peptide GT for Improving Hair Condition in Individuals with Damaged Hair: A Randomized, Double-Blind, Placebo-Controlled Trial International Journal of Stem Cells · 2026
    24. Treatment of androgenetic alopecia in transgender people receiving testosterone therapy with sublingual minoxidil: A randomized, double-blind, placebo-controlled clinical trial Journal of the American Academy of Dermatology · 2026
    25. Novel Vegan Exosome-like Biomimetic Vesicles for Skin and Hair Follicle Protection and Rejuvenation: Structural and Functional Characterization and Placebo-Controlled Clinical Efficacy Studies Cosmetics · 2026
    26. Is Spontaneous Regrowth in Alopecia Areata Possible: A Systematic Review and Meta-analysis of Placebo-controlled Studies Acta Dermato Venereologica · 2025
    27. Safety and Clinical Efficacy of KūlarisTM, an Herbal Supplement for Mild to Severe Acne Vulgaris – A 12-Week Randomized, Double Blind, Placebo-Controlled Study Clinical Cosmetic and Investigational Dermatology · 2025
    28. LB1139 AMP-303 injectable treatment for androgenetic alopecia: A multicenter, randomized, placebo-controlled feasibility study of a novel polysaccharide Journal of Investigative Dermatology · 2025
    29. Supplementary Material for: Sesquiterpene-Enriched Extract of <i>Curcuma aeruginosa</i> Roxb. Retards Axillary Hair Growth: A Randomised, Placebo-Controlled, Double-Blind Study Figshare · 2018
    30. Evaluation of Platelet Rich Plasma for Treatment of Female Pattern Hair Loss: A Placebo-Controlled Case Study Journal of Dermatology Research · 2022