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Glossary Nocebo Effect

negative expectations cause adverse symptoms despite inactive treatment

The nocebo effect occurs when negative expectations or beliefs about a treatment or condition cause a person to experience adverse symptoms or a worsening of their condition, even if the treatment is inactive or harmless. For example, if someone believes that a harmless cream will cause skin irritation, they might actually develop a rash due to their negative expectations. This phenomenon is the opposite of the placebo effect, where positive expectations lead to perceived or actual improvements in health.

Research

5 / 121 results

research Finasteride 5mg and Sexual Side Effects: How Many of these are Related to a Nocebo Phenomenon?

225 citations , July 2007 in “The Journal of Sexual Medicine”

In this study, patients informed about finasteride's potential sexual side effects reported a significantly higher occurrence of these side effects, suggesting a nocebo effect.

research The nocebo effect: A clinicians guide

41 citations , October 2012 in “Australian and New Zealand Journal of Psychiatry”

Negative expectations can cause adverse effects in patients even without active treatment, and managing this nocebo effect involves better communication and patient-clinician relationships.

research Nocebo effect in Dermatology

12 citations , January 2015 in “Indian Journal of Dermatology, Venereology and Leprology”

This review discusses the nocebo effect in dermatology, highlighting its mechanisms, implications, and strategies to manage it, but does not provide new clinical research findings.

research Many sexual adverse effects of finasteride are attributable to a nocebo effect

1 citations , February 2008 in “Nature Clinical Practice Urology”

Finasteride's sexual side effects may be due to nocebo effect.

research T07-O-05 Finasteride 5 mg and sexual side effects. How many of these are related to a nocebo phenomenon?

April 2008 in “Sexologies”

In this study, patients who were informed about finasteride's sexual side effects reported them significantly more often than those who were not, highlighting a potential nocebo effect.

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Community Join

5 / 423 results

community What percentage of people getting sides from Fin do you think is actually due to Nocebo ?

in Finasteride/Dutasteride 7 upvotes 1 month ago

Many users believe the nocebo effect contributes to perceived side effects of finasteride, with some attributing libido changes to pre-existing conditions rather than the drug itself. While some report genuine side effects, others suggest these are overrepresented or imagined, emphasizing the importance of understanding one's baseline health before starting treatment.

community Experiencing Side Effects on Fluridil After 8 Days – What to Do?

in Basic Questions 137 upvotes 3 months ago

The user is experiencing side effects from fluridil after switching from finasteride due to severe side effects. They are uncertain whether to continue with fluridil, considering it might be their body adjusting, a nocebo effect, or a permanent issue.

community Experiencing Side Effects 3 Days into Topical Fin; Long-term Topical Min User Seeking Advice on Dosage

in Finasteride 78 upvotes 7 months ago

The user started using topical finasteride three days ago alongside minoxidil and is experiencing testicular pain, which they believe is a nocebo effect. They are anxious about the dosage and seeking advice on whether increasing the application frequency affects the overall dosage.

community The Placebo Group Has It Worse Than The Standard Prescription 0.5mg Group. -The fear is all in your head.

190 upvotes 1 year ago

Dutasteride at 0.5mg may have fewer sexual side effects than expected, with many side effects attributed to psychological factors (nocebo effect). The placebo group experienced more side effects, suggesting fear and anxiety might contribute to perceived side effects.

community EU Shouldn't Ban Fin & Dut: PFS is NOT REAL.

10 upvotes 1 year ago

Finasteride and Dutasteride do not cause depression or "Post Finasteride Syndrome," with concerns often linked to the nocebo effect and preexisting mental health issues. The EU is unlikely to ban these drugs, but access may become more restricted due to ongoing debates.

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