Comment on Current Investigations into Postfinasteride Syndrome

    Ralph M. Trüeb, Ngoc-Nhi Catharina Luu, Natalia Caballero-Uribe, R. Dias, Hudson Dutra Rezende
    TLDR Finasteride is effective for hair regrowth, but some believe it may cause persistent symptoms due to psychological factors.
    The document examines the effects of male pattern hair loss and the use of finasteride, highlighting its effectiveness in hair regrowth with an 87.1% positive response rate in a study of 3,177 Japanese men. Despite its benefits, the controversial Postfinasteride Syndrome (PFS) is discussed, characterized by persistent symptoms after discontinuation. The medical community largely attributes PFS to psychological factors, with some suggesting it may be an induced delusional disorder influenced by media and nocebo effects. The authors emphasize the importance of patient understanding and mental health considerations in treatment decisions, advocating for a balanced approach to finasteride use.
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