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Did you mean Post-Finasteride Syndrome?

Glossary Post-Finasteride Syndrome

condition with persistent side effects after stopping finasteride

Post-Finasteride Syndrome (PFS) is a condition that some individuals experience after discontinuing the use of finasteride, a medication commonly prescribed for hair loss and benign prostatic hyperplasia. Symptoms can include persistent sexual dysfunction, depression, anxiety, and cognitive impairments, which may continue for months or even years after stopping the drug. The exact cause of PFS is not well understood, and it remains a topic of ongoing research and debate within the medical community.

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Research

5 / 496 results

Comment on Current Investigations into Postfinasteride Syndrome

research Comment on Current Investigations into the Postfinasteride Syndrome

January 2024 in “International Journal of Trichology”

The authors concluded that the concept of postfinasteride syndrome remains contentious and may be more plausibly characterized as a psychiatric condition rather than a consistent medical syndrome.

How to Deal with the Issues of Fertility, Malignancies, and Postfinasteride Syndrome While Prescribing Finasteride for Male Pattern Hair Loss

research How to Deal with the Issues of Fertility, Malignancies, and the Postfinasteride Syndrome while Prescribing Finasteride for Male Pattern Hair Loss

January 2022 in “Skin appendage disorders”

The researchers concluded that while oral finasteride is effective and generally safe for treating male pattern hair loss, careful patient selection and risk assessment are important to address potential concerns such as fertility issues and mental health risks.

research Post-finasteride syndrome: An emerging clinical problem

26 citations , December 2019 in “Neurobiology of Stress”

This review discusses adverse effects of 5 alpha-reductase inhibitors, particularly persistent side effects such as post-finasteride syndrome, and highlights the need for further investigation.

research Post-finasteride syndrome

11 citations , August 2019 in “BMJ”

This article reviews ongoing concerns about the safety of 5α-reductase inhibitors like finasteride, highlighting the lack of long-term data on persistent depression and sexual side effects after drug discontinuation; no new clinical results are reported.

research A comment on the post-finasteride syndrome

11 citations , January 2018 in “International Journal of Trichology”

This commentary reviews the post-Finasteride syndrome and argues that while the condition's validity is debated, comprehensive guidelines are needed to address related risks and treatment options; it reports no new clinical results.

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Community Join

5 / 181 results

community So it turns out Post Finasteride Syndrome was never real?

in Finasteride/Dutasteride 271 upvotes 2 years ago

Post Finasteride Syndrome (PFS) is debated, with some users reporting severe side effects from finasteride, while others believe these effects are rare or psychosomatic. Treatments discussed include finasteride, minoxidil, and RU58841.

community if Post Finasteride Syndrome is real. Why is it only the negative effects and not positive have log term effect?

in Finasteride/Dutasteride 63 upvotes 4 months ago

Finasteride is used for hair loss, with mixed reports of no side effects and claims of long-term negative effects known as Post Finasteride Syndrome (PFS). The conversation debates the existence and causes of PFS, with differing opinions on whether it is psychological or real.

community Going on what I’ve read fixing e2 (estradiol) levels should cure PFS (post finasteride syndrome)?

4 upvotes 4 years ago

Balancing estradiol (e2) levels may alleviate post-finasteride syndrome (PFS) symptoms. Hormone tests, including testosterone and e2, are recommended for those experiencing PFS.

community White Rice Lowers DHT and might cause post finasteride syndrome

in Finasteride/Dutasteride 4 years ago

White rice may lower DHT and potentially cause symptoms similar to post-finasteride syndrome. The user experienced muscle wasting, depression, and other symptoms after consuming large amounts of white rice.

community Trying to understand finasteride side effects and post finasteride syndrome

70 upvotes 5 years ago

The conversation discusses the side effects of finasteride, including low libido and erectile dysfunction, and the possibility of these effects being permanent, known as post-finasteride syndrome (PFS). Some users report personal experiences with PFS and debate whether the condition is real, with varying opinions on the reversibility of side effects and the role of individual biology.

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Learn

3 / 801 results

learn Dutasteride

Heavy duty finasteride that comes with higher risks

Dutasteride side effects: what the label and studies actually report The Avodart label reports impotence in 4.7% and decreased libido in 3.0% of men in the first six months (1.7% and 1.4% on placebo), with new reports falling after month six; those figures come from BPH trials in older men, and the hair-loss trials in younger men run only six months. The label and studies also flag a PSA drop of about half, a small rise in high-grade prostate cancer in one trial, an observational link to depression, and sexual effects that the label says may persist after stopping.

learn Finasteride

Frontline, gold standard treatment for combatting androgenic alopecia

Is finasteride safe? Studies report that most men tolerate finasteride 1 mg, but case series, regulatory labelling and patient reports describe sexual, mood and cognitive effects that some say persisted after stopping, and how often that happens is not established. It is a prescription-only medicine and is contraindicated in pregnancy.
Does stopping finasteride mean losing all progress? Here's what really happens. Studies and the drug label report that finasteride's benefit lasts only while it is taken: after stopping, scalp DHT returns to baseline and hair loss resumes over roughly 6 to 12 months. Stopping a prescription drug is a decision to make with the prescriber.
Finasteride Results Timeline: How Long It Takes to Work, Shedding Phases, and Expected Outcomes Trial data and community reports both put the first visible changes on finasteride at roughly 3 to 6 months, with the clearest results between 6 and 12 months; an early shedding phase is common and usually temporary. The benefit lasts only while the drug is taken, and it is prescription-only.
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learn Saw Palmetto

a natural and far less effective alternative to Finasteride

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