Post-Finasteride Syndrome: When Will We Get the Courage to Fight the Dictating Pharma Industry Despite Awareness of Sexual, Neurological, and Metabolic Side Effects in Young Men for Over a Decade

    January 2020 in “ Archives of urology ”
    Kulvinder Kochar Kaur, Gautam Allahbadia, Mandeep Singh
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    TLDR Finasteride, a drug used for certain conditions, can cause serious side effects like sexual dysfunction, suicidal thoughts, and increased diabetes risk, and there's a need for more awareness and research about these effects.
    The 2019 document reviewed Post-Finasteride Syndrome (PFS), a condition that can develop after stopping the drug Finasteride, used for benign prostatic hyperplasia and androgenic alopecia. The review emphasized serious side effects including persistent sexual dysfunctions, suicidal ideation, and metabolic effects like the risk of developing type 2 diabetes mellitus. The authors criticized the medical community's slow response to these side effects and potential biases in studies funded by the drug manufacturer. They called for a change in attitude towards these side effects and more research into PFS's pathophysiology. The document also discussed studies showing a link between finasteride use and erectile dysfunction, mood alterations, and other side effects. Despite these findings, some studies found finasteride safe and tolerable, with minimal or no side effects. The authors stressed the need for more awareness and understanding of these side effects in the medical community.
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