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    Follistatin

    also sh-Polypeptide-86

    Follistatin, also known as activin-bindings protein, is a protein that in humans is encoded by the FST gene. Follistatin is an autocrine glycoprotein that is expressed in nearly all tissues of higher animals.

    Information, not medical advice. Talk to a licensed doctor or pharmacist before starting or changing a treatment.

    Research 10

    1. Successful Treatment of Female Pattern Hair Loss with Injection of Autologous Adipose-derived Adult Stem Cells: A Controlled Clinical, Trichoscopic, and Immunohistochemical Trial International Journal of Trichology · 2025
    2. New intranasal and injectable gene therapy for healthy life extension bioRxiv (Cold Spring Harbor Laboratory) · 2021
    3. The Thinning Top: Why Old People Have Less Hair Journal of Investigative Dermatology · 2014 · 4 citations
    4. Impaired wound healing in transgenic mice overexpressing the activin antagonist follistatin in the epidermis EMBO journal · 2001 · 163 citations
    5. Characterization and isolation of stem cell-enriched human hair follicle bulge cells 2005 · 550 citations
    6. Control of pelage hair follicle development and cycling by complex interactions between follistatin and activin The FASEB Journal · 2003 · 81 citations
    7. Secreted Frizzled‐Related Protein 2 ( SFRP2 ) Induces Follistatin‐Like 1 ( FSTL1 ) to Regulate Dihydrotestosterone ( DHT )‐Induced Dermal Papilla Cell Mitochondrial Dysfunction and Senescence Aging Cell · 2026
    8. Regenerative Hair Waves in Aging Mice and Extra-Follicular Modulators Follistatin, Dkk1, and Sfrp4 Journal of Investigative Dermatology · 2014 · 75 citations
    9. A counter gradient of Activin A and follistatin instructs the timing of hair cell differentiation in the murine cochlea eLife · 2019 · 15 citations
    10. Author response: A counter gradient of Activin A and follistatin instructs the timing of hair cell differentiation in the murine cochlea 2019
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    Community 2

    1. Follistatin, thoughts about a potential treatment ? Reddit · 10 Sept 2023
    2. Hair Regrowth Following a Wnt- and Follistatin- Containing Treatment: Safety and Efficacy in a First-in-Man Phase 1 Clinical Trial: Scientific, Peer-Reviewed Dermatology Article Indexed with MEDLINE/PubMed Reddit · 4 Jun 2014
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