Sp6 Downregulation of Follistatin Gene Expression in Ameloblasts

    January 2008 in “ Journal of medical investigation ”
    Intan Ruspita, Keiko Miyoshi, Taro Muto … Takafumi Noma
    Studysummary This study found that Sp6 overproduction in ameloblast-lineage cells increased cell proliferation and ameloblastin expression, suggesting that Sp6 promotes amelogenesis by inhibiting follistatin gene expression.
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    1. The Krüppel-Like Factor Epiprofin Is Expressed by Epithelium of Developing Teeth, Hair Follicles, and Limb Buds and Promotes Cell Proliferation Journal of Biological Chemistry · 2003

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    1. Sp6 Downregulation of Follistatin Gene Expression in Ameloblasts Journal of medical investigation · 2008