The Role of Activins and Follistatins in Skin and Hair Follicle Development and Function

    October 2008 in “ Cytokine & Growth Factor Reviews ”
    M. McDowall, Natalie Edwards, Colin A.B. Jahoda, P. I. Hynd
    Studysummary This review discusses the role of activin signaling in hair follicle formation, hair growth cycling, and skin healing, but presents no new clinical findings.
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    Research cited in this study 11

    1. The Role of Smads in Skin Development ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2008
    2. Too Many Follistatins: Racing Inside and Getting Out of the Cell Endocrinology · 2005
    3. Activin Controls Skin Morphogenesis and Wound Repair Predominantly via Stromal Cells and in a Concentration-Dependent Manner via Keratinocytes ˜The œAmerican journal of pathology · 2005
    4. Molecular Biology of Hair Morphogenesis: Development and Cycling Journal Of Experimental Zoology Part B: Molecular And Developmental Evolution · 2003
    5. Control of Pelage Hair Follicle Development and Cycling by Complex Interactions Between Follistatin and Activin The FASEB Journal · 2003
    6. Molecular Mechanisms Regulating Hair Follicle Development ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2002
    7. Impaired Wound Healing in Transgenic Mice Overexpressing the Activin Antagonist Follistatin in the Epidermis EMBO journal · 2001
    8. The Roles of Activins in Repair Processes of the Skin and the Brain Molecular and cellular endocrinology · 2001
    9. Overexpression of Activin A in the Skin of Transgenic Mice Reveals New Activities in Epidermal Morphogenesis, Dermal Fibrosis, and Wound Repair EMBO journal · 1999
    10. The Biology of Hair Follicles The New England Journal of Medicine · 1999
    11. Dermal-Epidermal Interactions in Hair Follicle Development and Cycling Clinics in dermatology · 1988