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GlossaryFollistatin

protein that inhibits activins, influencing muscle growth and hair

Follistatin, also known as FS or FST, is a protein that plays a crucial role in regulating various biological processes by binding to and inhibiting members of the TGF-beta superfamily, particularly activins. This inhibition is important for controlling muscle growth, inflammation, and tissue repair. In the context of hair biology, follistatin has been studied for its potential to promote hair growth and counteract conditions like alopecia by modulating the activity of growth factors involved in hair follicle development.

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learn Follistatin

glycoprotein that inhibits TGF-β and promotes hair growth by antagonizing activin

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research The Role of Activins and Follistatins in Skin and Hair Follicle Development and Function

45 citations, October 2008 in “Cytokine & Growth Factor Reviews”

Activins and follistatins, part of the TGFβ family, are crucial for hair follicle development and skin health, affecting growth, repair, and the hair cycle.

Fetal Programming of Polycystic Ovary Syndrome by Androgen Excess: Evidence from Experimental, Clinical, and Genetic Association Studies

research Fetal Programming of Polycystic Ovary Syndrome by Androgen Excess: Evidence from Experimental, Clinical, and Genetic Association Studies

253 citations, March 2006 in “The Journal of Clinical Endocrinology and Metabolism”

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

Overexpression of Activin A in the Skin of Transgenic Mice Reveals New Activities in Epidermal Morphogenesis, Dermal Fibrosis, and Wound Repair

research Overexpression of Activin A in the Skin of Transgenic Mice Reveals New Activities in Epidermal Morphogenesis, Dermal Fibrosis, and Wound Repair

204 citations, October 1999 in “EMBO journal”

Overexpression of activin A in mice skin causes skin thickening, fibrosis, and improved wound healing.

research Growth Factors in Hair Organ Development and the Hair Growth Cycle

90 citations, October 1996 in “Dermatologic Clinics”

Growth factors are crucial for hair development and could help treat hair diseases.

research A New Path in Defining Light Parameters for Hair Growth: Discovery and Modulation of Photoreceptors in Human Hair Follicle

70 citations, April 2017 in “Lasers in surgery and medicine”

Blue light promotes hair growth by interacting with specific receptors in hair follicles.

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community Follistatin, thoughts about a potential treatment ?

in Research/Science 7 upvotes 1 year ago

Follistatin, known for inhibiting myostatin and promoting muscle growth in mice, is being discussed as a potential treatment for hair loss. Specific treatments mentioned include Minoxidil, Finasteride, and RU58841.

community Injections of follistatin and growth factors shown to improve hair growth in study

6 upvotes 12 years ago

Injections of follistatin and growth factors can improve hair growth. Specific treatments discussed include Minoxidil, finasteride, and RU58841.

community Hair Regrowth Following a Wnt- and Follistatin- Containing Treatment: Safety and Efficacy in a First-in-Man Phase 1 Clinical Trial: Scientific, Peer-Reviewed Dermatology Article Indexed with MEDLINE/PubMed

4 upvotes 10 years ago

A treatment containing Wnt and Follistatin was found to be safe and effective for hair regrowth in a Phase 1 clinical trial. Specific treatments discussed include Minoxidil, Finasteride, and RU58841.