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    GlossaryHair Follicle Development

    process where hair follicles form and mature through cellular events

    Hair follicle development, also known as hair follicle morphogenesis, is the process by which hair follicles form and mature. This involves a complex interplay of genetic, molecular, and cellular events that begin in the embryonic stage and continue through life. Key stages include the initiation of follicle placodes, the formation of hair germs, and the differentiation of various cell types that make up the follicle, ultimately leading to the production of hair shafts.

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      learn Valproic acid

      an anticonvulsant repurposed for hair loss via histone inhibition

      learn Follistatin

      glycoprotein that inhibits TGF-β and promotes hair growth by antagonizing activin

      learn KY19382

      compound that activates Wnt/β-catenin to promote hair regrowth and create new hair follicles

      learn Exosomes

      Microscopic delivery system that sends growth-promoting signals to hair follicles

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      community Keratin microspheres - breakthrough

      in Research/Science  14 upvotes 1 year ago
      A gel of keratin microspheres promotes hair follicle growth, showing similar effectiveness to minoxidil in mice. The treatment activates hair growth pathways and reduces inflammation, with potential applications in drug delivery for hair-related disorders.

      community Better Than Minoxidil? Topical Sodium Valproate

      in Research/Science  52 upvotes 1 month ago
      Topical sodium valproate may promote hair growth by inhibiting GSK3β, allowing beta-catenin to proliferate, but it has potential side effects and requires more research. The conversation also mentions skepticism about a product called Vdphlo1, which includes sodium valproate and other ingredients.

      community Anyone Try Microneedling with Exosomes/AAPE?

      in Microneedling  2 upvotes 2 years ago
      User asks where to purchase exosomes/AAPE for microneedling hair loss treatment. Links to research on hair regeneration therapy, stem cell therapy, exosome therapy, and dermal exosomes provided.

      community Nice product I discovered, thought I would share.

      in Treatment  415 upvotes 2 days ago
      A product that makes hair look thicker and healthier without promoting regrowth. Discussions include treatments like minoxidil, finasteride, red light therapy, and a serum with caffeine and peptides, with mixed effectiveness opinions.