23 citations
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May 1998 in “Journal of Dermatological Science”
This study suggests that skin sections from 4-week-old C3H mice could serve as an in vitro model for human androgenic alopecia, as minoxidil partially reverses suppressed hairfollicleelongation.
10 citations
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January 2004 in “Dermatologic Surgery”
This study found that storing hairfollicle micrografts in HEPES-buffered DMEM with ACD inhibitors like aminoguanidine significantly increased hair shaft elongation compared to phosphate-buffered salt solution, suggesting improved viability for transplantation.
April 2018 in “Journal of Investigative Dermatology”
This study found that dermal white adipose tissue surrounding human hairfollicles enhances proliferation, pigmentation, and hair shaft elongation in an ex vivo setting.
Cannabis and THC may have mixed effects on hair, with some studies suggesting potential negative impacts on hair growth in isolated hairfollicles, but these results are hard to apply to living humans. Treatments like minoxidil and finasteride are commonly used for hair loss, and the effects of cannabis might be neutral or vary based on individual factors.
Caffeine in hair care can support hair growth but is not a standalone solution; it's best used in combination with other treatments like minoxidil and finasteride. Some products combine caffeine with these treatments for enhanced effects.
The conversation discusses hair loss linked to BDNF-increasing nootropics like Semax and Lions Mane. Suggested topical treatments include capsaicin, beta-glucan, and ginseng to counteract TGF-B activation.
Peptides like TB500, KPV, GHK-CU, and BPC-157 are overhyped for hair growth with limited proven effectiveness in humans. Combining peptides with delivery methods like iontophoresis and sonophoresis shows promise, but many claims remain unproven.
Hair transplantation moves DHT-resistant follicles from a donor area (back and sides of the scalp) into thinning or bald areas. The transplanted hair is generally permanent, though surrounding native hair can keep thinning.