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    Clascoterone

    also Breezula, CB-03-01, Winlevi

    Clascoterone, sold under the brand name Winlevi, is an antiandrogen medication which is used topically in the treatment of acne. The medication is used as a cream by application to the skin, for instance the face and scalp. Clascoterone is an antiandrogen, or antagonist of the androgen receptor (AR), the biological target of androgens such as testosterone and dihydrotestosterone. It shows minimal systemic absorption when applied to skin.

    Information, not medical advice. Talk to a licensed doctor or pharmacist before starting or changing a treatment.

    Research 10

    1. 0951 Breezula, a clinical stage topical anti-androgen, promotes dermal papilla inductivity and reduces IL-6 secretion in balding skin samples ex vivo Journal of Investigative Dermatology · 2025
    2. A Phase 1 Study to Investigate the Effects of Cortexolone 17α‐Propionate, Also Known as Clascoterone, on the QT Interval Using the Meal Effect to Demonstrate ECG Assay Sensitivity Clinical Pharmacology in Drug Development · 2021 · 2 citations
    3. Living Probiotic Microneedles Coordinate Antiandrogen and Nitric Oxide Therapy for Androgenetic Alopecia ACS Applied Materials & Interfaces · 2026
    4. Clascoterone: First Approval Drugs · 2020 · 27 citations
    5. Cortexolone 17a-propionate: A new antiandrogen acting on hair dermal papilla cells for the treatment of androgenic alopecia Journal of The American Academy of Dermatology · 2014
    6. Use of topical clascoterone for the treatment of hidradenitis suppurativa JAAD Case Reports · 2023 · 10 citations
    7. Differential diagnosis of trichotillomania by trichoscopy Journal of The American Academy of Dermatology · 2014
    8. Androgens and acne: perspectives on clascoterone, the first topical androgen receptor antagonist Expert opinion on pharmacotherapy · 2021 · 9 citations
    9. Androgenetic alopecia: An update JAAD International · 2023
    10. Androgenetic Alopecia in Women: A Narrative Review of Pathophysiology, Clinical Evaluation, and Treatments American Journal of Clinical Dermatology · 2026
    All research on Clascoterone →

    Community 10

    1. Clascoterone Phase 3 Results and Efficacy Reddit · 22 Sept 2026
    2. I Get Side-Effects from Anti-Androgens Reddit · 9 Sept 2020
    3. Why isn’t Clascoterone being discussed more? Reddit · 18 Sept 2026
    4. What has the evidence been on side effects with CB? Reddit · 25 Jul 2020
    5. Winlevi Clascoterone- resultssss Reddit · 15 Sept 2026
    6. M20 with Hair Loss - Clascoterone an Option? Community · 3 Apr 2026
    7. Whatever happened to Clascoterone? (breezula for hair) (sold as Winlevi for acne available since 2021) Reddit · 3 Sept 2026
    8. Has anyone tried CB-01-03 aka Clascoterone? Reddit · 9 Mar 2026
    9. Clascoterone full results 2026 Reddit · 1 Sept 2026
    10. Why is everyone still arguing about PP405 when clascoterone is already heading toward regulatory submission? Reddit · 13 Aug 2026
    All community posts on Clascoterone →