Androgenetic Alopecia: Therapy Update

    May 2023 in “ Drugs
    Shivali Devjani, Ogechi Ezemma, Kristen J. Kelley, Emma Stratton, Maryanne M. Senna
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    TLDR There are many treatments for common hair loss, but more trials are needed to decide which are best.
    Androgenetic Alopecia (AGA), a common form of hair loss, affects 80% of men and 50% of women by age 70. The FDA has approved two drugs for AGA: topical minoxidil and oral finoxidil. Other treatments include topical finasteride, dutasteride, oral minoxidil, spironolactone, flutamide, bicalutamide, clascoterone, pyrilutamide, and injectable treatments like botulinum A toxin and dutasteride mesotherapy. Non-drug treatments include Platelet-Rich Plasma (PRP) treatment, Low-Level Light Therapy (LLLT), mesenchymal stem cells (MSCs), microneedling, and nutritional supplements. The document concludes that more large-scale, double-blinded, placebo-controlled randomized trials are needed to make informed decisions about AGA treatments.
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