TLDR Botulinum toxin injections may help treat hair loss by blocking harmful secretion in hair follicles.
The study evaluated the efficacy and safety of intradermal injection of botulinum toxin (BTX) in treating androgenetic alopecia (AGA) and its relationship with transforming growth factor-B1 (TGF-B1). The study found that BTX successfully abrogated DHT-induced secretion of TGF-ß1 from dermal papilla cells (DPC) and was effective against AGA by inhibiting TGF-ß1 secretion in the hair bulb, which is thought to suppress follicular keratinocyte growth and changes in the hair cycle. The study suggests that intradermal injection of botulinum toxin could be a possible treatment option for AGA by inhibiting TGF-ß1 secretion from the hair follicles. However, further research and long-term follow-up are required. The study comprised 18 male patients with a mean age of 49.00 ± 6.50.
24 citations,
January 2017 in “Journal of Cutaneous and Aesthetic Surgery” Botulinum toxin was found to be a safe and effective treatment for male pattern baldness in a small test, but more research is needed.
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November 2010 in “Journal of Dermatological Science” Male pattern baldness involves hormones and cell signals affecting hair growth.
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May 2007 in “Journal of The American Academy of Dermatology” The BASP classification is a detailed and accurate way to categorize hair loss in both men and women.
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September 2022 in “Evidence-based Complementary and Alternative Medicine” Gardenia florida fruit extract may help hair grow and needs more research to understand how.
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November 2020 in “Frontiers in Cell and Developmental Biology” The "Two-Cell Assemblage" assay is a new, simple method to identify substances that may promote hair growth.
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September 2020 in “Frontiers in Microbiology” Algal oligosaccharides help prevent hair loss and promote hair growth.
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April 2020 in “Journal of The American Academy of Dermatology” Botulinum toxin injections may help treat hair loss by blocking harmful secretion in hair follicles.
Padina arborescens and its component MOGG may help prevent hair loss through several actions, including blocking a hair loss-related enzyme.
190 citations,
October 2002 in “The FASEB journal” Androgens may cause hair loss by increasing TGF-beta1 from scalp cells, which inhibits hair cell growth.
