Spironolactone for Treatment of Female Pattern Hair Loss

This study reported that once-daily treatment with oral minoxidil and spironolactone for 12 months reduced hair loss severity and hair shedding in women with pattern hair loss, with generally mild side effects, though results came from an uncontrolled, observational pilot study.

In this study, spironolactone was reported to stabilize or improve female pattern hair loss in 74.3% of treated women, especially those with signs of hyperandrogenism.

This review assessed available treatments for female pattern hair loss and found that minoxidil improved hair regrowth compared to placebo, though high-quality evidence was limited for other interventions.

This review discusses therapeutic options for androgenetic alopecia, noting that while antiandrogen treatments prevent further hair loss and promote some regrowth, dramatic results are rare.

This study found that 88% of women with female pattern hair loss who received oral antiandrogens saw no progression or improvement in their condition.