TLDR Tofacitinib and oral minoxidil may help treat Sisaipho alopecia areata.
A study explored the treatment of Sisaipho alopecia areata, a rare variant of AA characterized by hair loss on the top of the scalp while sparing the temporal and occipital areas, using tofacitinib and oral minoxidil. The combination of these treatments showed promise in managing this challenging condition, which typically presents as nonscarring hair loss and can be difficult to treat.
23 citations,
September 2019 in “Journal of The American Academy of Dermatology” Tofacitinib and oral minoxidil together effectively regrow hair in severe alopecia areata patients.
130 citations,
February 2018 in “Journal of Investigative Dermatology” Tofacitinib may help treat severe hair loss, but more research is needed.
Tofacitinib helped a woman with total-body hair loss grow her hair back.
24 citations,
January 2018 in “International Journal of Trichology” Tofacitinib helped regrow hair in patients with alopecia, with few side effects.
16 citations,
July 2017 in “Rheumatology and Therapy” Tofacitinib, a medication for arthritis, showed potential for treating severe hair loss in a small Brazilian case series, but more research is needed.
