Combination Tofacitinib and Oral Minoxidil Treatment for Severe Alopecia Areata

September 2019 in “ Journal of The American Academy of Dermatology ”

Carlos Gustavo Wambier, Brittany G. Craiglow, Brett A. King

tofacitinib oral minoxidil alopecia areata hair regrowth Rogaine

TLDR Tofacitinib and oral minoxidil together effectively regrow hair in severe alopecia areata patients.

The document titled "Combination tofacitinib and oral minoxidil treatment for severe alopecia areata" discusses various studies that explore the effectiveness of combining tofacitinib and oral minoxidil treatment for severe alopecia areata. The studies involved a range of patients with severe alopecia areata who were treated with a combination of tofacitinib and oral minoxidil. The results showed that the combination treatment led to significant hair regrowth in all patients, with no serious adverse effects reported. The studies suggest that the combination of tofacitinib and oral minoxidil may be a promising treatment option for severe alopecia areata.

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Research cited in this study

5 / 5 results

An Open-Label Pilot Study to Evaluate the Efficacy of Tofacitinib in Moderate to Severe Patch-Type Alopecia Areata, Totalis, and Universalis

research An Open-Label Pilot Study to Evaluate the Efficacy of Tofacitinib in Moderate to Severe Patch-Type Alopecia Areata, Totalis, and Universalis

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Tofacitinib may help treat severe hair loss, but more research is needed.

$Oral Tofacitinib Monotherapy in Korean Patients with Refractory Moderate-to-Severe Alopecia Areata: A Case Series$

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Tofacitinib is effective and safe for treating severe hair loss in Korean patients.

research Tofacitinib for the Treatment of Severe Alopecia Areata and Variants: A Study of 90 Patients

238 citations, November 2016 in “Journal of The American Academy of Dermatology”

Tofacitinib is effective and safe for severe hair loss, but full regrowth is less likely after 10 years of hair loss.

research Safety and Efficacy of the JAK Inhibitor Tofacitinib Citrate in Patients with Alopecia Areata

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Tofacitinib is safe and effective for severe alopecia areata, but hair loss may return 2 months after stopping treatment.

research Evaluation of Oral Minoxidil in the Treatment of Alopecia Areata

34 citations, November 1987 in “Archives of Dermatology”

Oral minoxidil helps hair regrowth in 80% of alopecia patients, but only 18% see cosmetic improvement.

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