A Novel Hope for Alopecia Totalis Patients: Case Report

    November 2020 in “ Dubai medical journal ”
    Mohamed A. Elsayed, Laila Al Otaibi, Nael Quraishy, Afzalhussein Yusufali
    Image of study
    TLDR Tofacitinib may effectively regrow hair in alopecia totalis patients.
    This case report described the treatment of a 24-year-old female patient with alopecia totalis (AT) using tofacitinib, a Janus kinase (JAK) inhibitor. The patient, who also had juvenile chronic arthritis, had not responded satisfactorily to other treatments over 3 years. She was administered tofacitinib 5 mg orally twice a day, resulting in noticeable hair regrowth starting from the 4th week and full regrowth by the 9th month, with no serious adverse effects. The findings suggested that tofacitinib could be an effective and well-tolerated treatment for AT, though larger studies were recommended to confirm its long-term efficacy.
    Discuss this study in the Community →

    Research cited in this study

    3 / 3 results

    Related Community Posts Join

    6 / 1000+ results

      community Alopecia Areata Question

      in Treatment  2 upvotes 3 years ago
      A user with alopecia totalis, borderline universalis, seeks advice on getting into a Xeljanz trial or appealing insurance for coverage. They experienced significant hair regrowth but are now seeing hair loss again and want to try Xeljanz.

      community Losing hair everywhere, idk what to do :(

       29 upvotes 6 years ago
      A 22-year-old male has been experiencing widespread hair loss for over four years, including pain and significant shedding. Treatments tried include ketoconazole shampoo, fluocinonide topical solution, biotin, ACV, and dry shampoo, but none have been effective.

      community This guy claims stem cells fixed his balding

      in Is this regrowth?  301 upvotes 1 year ago
      A man who claimed to have regrown his hair using stem cell treatment, sparking a debate about its effectiveness and cost. Some users suggested he might be using other treatments or substances, while others shared their own experiences with stem cell therapy for hair loss.

      community Shaving is NOT accepting baldness

      in Shaved/buzzed  52 upvotes 1 year ago
      Accepting baldness and the various ways people try to cope with it, such as shaving, using medications like minoxidil and finasteride, or getting a hair transplant. Participants discussed how true acceptance of hair loss involves confronting difficult emotions such as grief for one's former appearance and identity, as opposed to simply superficially hiding it with a shaved head.

    Related Research

    9 / 9 results