Sequential High- And Low-Dose Systemic Corticosteroid Therapy For Severe Childhood Alopecia Areata

    January 2017 in “ Journal der Deutschen Dermatologischen Gesellschaft ”
    Karin Jahn‐Bassler, Wolfgang Bauer, Franz Karlhofer … Georg Stingl
    Studysummary This study reports that sequential high- and low-dose prednisolone therapy effectively promotes complete hair regrowth in 62% of children with severe alopecia areata, while minimizing severe side effects.
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    Research cited in this study 17

    1. Combined Oral Pulse and Topical Corticosteroid Therapy for Severe Alopecia Areata in Children: A Long-Term Follow-Up Study Dermatologic therapy · 2015
    2. Alopecia Areata Is Driven by Cytotoxic T Lymphocytes and Is Reversed by JAK Inhibition Nature medicine · 2014
    3. Killing Two Birds with One Stone: Oral Tofacitinib Reverses Alopecia Universalis in a Patient with Plaque Psoriasis Journal of Investigative Dermatology · 2014
    4. Overview of Alopecia Areata ˜The œjournal of investigative dermatology. Symposium proceedings/˜The œJournal of investigative dermatology symposium proceedings · 2013
    5. Pulse Corticosteroid Therapy for Alopecia Areata in Children: A Retrospective Study Dermatology · 2013
    6. British Association of Dermatologists’ Guidelines for the Management of Alopecia Areata 2012 British Journal of Dermatology · 2012
    7. Alopecia Areata: An Autoimmune Disease Causing Hair Loss The New England Journal of Medicine · 2012
    8. Late-Onset Alopecia Areata: A Retrospective Study of 73 Patients from Taiwan Journal of the European Academy of Dermatology and Venereology · 2012
    9. Efficacy and Tolerability of Methotrexate in Severe Childhood Alopecia Areata British journal of dermatology/British journal of dermatology, Supplement · 2011
    10. The Pathogenesis of Primary Cicatricial Alopecias The American Journal of Pathology · 2010
    11. Maintenance of Hair Follicle Immune Privilege Is Linked to Prevention of NK Cell Attack Journal of Investigative Dermatology · 2007
    12. Placebo-Controlled Oral Pulse Prednisolone Therapy in Alopecia Areata Journal of the American Academy of Dermatology · 2005
    13. Twice Weekly 5 mg Dexamethasone Oral Pulse in the Treatment of Extensive Alopecia Areata The Journal of Dermatology · 1999
    14. Treatment of Widespread Alopecia Areata in Young Patients with Monthly Oral Corticosteroid Pulse Pediatric Dermatology · 1998
    15. Systemic Steroids With or Without 2% Topical Minoxidil in the Treatment of Alopecia Areata Archives of Dermatology · 1992
    16. Failure of Passive Transfer of Serum From Patients With Alopecia Areata and Alopecia Universalis to Inhibit Hair Growth in Transplants of Human Scalp Skin Grafted Onto Nude Mice British Journal of Dermatology · 1992
    17. Juvenile Versus Maturity-Onset Alopecia Areata: A Comparative Retrospective Clinical Study Clinical and Experimental Dermatology · 1989

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