Juvenile Versus Maturity-Onset Alopecia Areata: A Comparative Retrospective Clinical Study

    November 1989 in “ Clinical and Experimental Dermatology ”
    F.B. WAARD-VAN DER SPEK, A. P. Oranje, D.M.J. De Raeymaecker, J. D. R. Peereboom‐Wynia
    TLDR Juvenile alopecia areata is more severe and has a worse prognosis than maturity-onset alopecia areata.
    This retrospective study analyzed 209 patients with alopecia areata (AA) to compare juvenile and maturity-onset cases. It found that juvenile AA was more severe and had a poorer prognosis than maturity-onset AA. No significant differences were observed between the groups regarding AA type and auto-antibody prevalence. Poor prognostic indicators included early onset, atopy, and ophiasis or onychodystrophy. Initial thyroid function tests were recommended, along with hair-root examination, thyroid antibody determination, and serum zinc level assessment. Psychosomatic factors were noted in 29% of juvenile and 17% of maturity-onset AA patients.
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