Treatment of Widespread Alopecia Areata in Young Patients with Monthly Oral Corticosteroid Pulse

    July 1998 in “ Pediatric Dermatology ”
    Vinod Sharma, S Muralidhar
    TLDR Monthly oral corticosteroid pulses effectively treat widespread alopecia areata in young patients.
    The study involved 16 young patients (up to 18 years old) with widespread alopecia areata (AA), divided into two age groups. Group A (12-18 years) received 300 mg of prednisolone monthly, while Group B (3-11 years) received betamethasone sodium phosphate equivalent to 5 mg/kg prednisolone monthly. Treatment continued for at least three doses or until satisfactory hair growth was achieved. At 6 months, 60% of patients showed excellent hair growth. During follow-up, 4 out of 13 patients experienced localized relapse. Side effects were minimal, with only two patients reporting transient issues. The study recommended pulsed prednisolone as an effective treatment for widespread AA in young patients.
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