Successful Treatment of Severe Alopecia Areata With Oral or Topical Tofacitinib

July 2018 in “ PubMed ”

Michelle Cheng, Amy Kehl, Scott Worswick, Carolyn Goh

alopecia areata tofacitinib Janus kinase inhibitor topical tofacitinib oral tofacitinib JAK inhibitor

TLDR Oral and topical tofacitinib can help regrow hair in people with severe alopecia areata.

The document presents a case series of 11 patients with severe alopecia areata who were treated with oral tofacitinib, a Janus kinase inhibitor. These patients experienced significant hair regrowth. Additionally, the document reports a case of moderate to severe alopecia areata successfully treated with topical tofacitinib cream. This suggests that both oral and topical tofacitinib can be effective treatments for severe alopecia areata.

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