Acne Exacerbation After Tofacitinib Treatment for Alopecia Areata

    January 2022 in “ Dermatology Reports ”
    Sawsan A Alharthi, Mohammed G. Turkmani, Mohammed I. AlJasser
    Studysummary This report describes a case where the JAK inhibitor tofacitinib led to hair regrowth in a patient with alopecia totalis but also worsened facial acne, highlighting a unique adverse effect.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 9

    1. JAK Inhibitors for the Treatment of Alopecia Areata PubMed · 2020
    2. Emerging Topical and Systemic JAK Inhibitors in Dermatology Frontiers in Immunology · 2019
    3. Benefit and Risk Profile of Tofacitinib for the Treatment of Alopecia Areata: A Systematic Review and Meta-Analysis Journal of the European Academy of Dermatology and Venereology · 2019
    4. Janus Kinase Inhibitors for the Treatment of Severe Alopecia Areata: An Open-Label Comparative Study Dermatology · 2018
    5. Janus Kinase Inhibitors in Dermatology: A Systematic Review Journal of the American Academy of Dermatology · 2017
    6. JAK Inhibitors in Dermatology: The Promise of a New Drug Class Journal of the American Academy of Dermatology · 2017
    7. Janus Kinase (JAK) Inhibitors for the Treatment of Skin and Hair Disorders: A Review of Literature Journal of Dermatological Treatment · 2016
    8. Tofacitinib for the Treatment of Severe Alopecia Areata and Variants: A Study of 90 Patients Journal of The American Academy of Dermatology · 2016
    9. Reversal of Alopecia Areata Following Treatment With the JAK1/2 Inhibitor Baricitinib EBioMedicine · 2015

    Related research 1

    1. Successful Treatment of Severe Alopecia Areata With Oral or Topical Tofacitinib PubMed · 2018