Treatment of Female Pattern Hair Loss with a Combination of Spironolactone and Minoxidil

    January 2007 in “ Australasian Journal of Dermatology ”
    Carlijn Hoedemaker, Sylvia L. van Egmond, Rodney Sinclair
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    TLDR Spironolactone and minoxidil together effectively treat female pattern hair loss.
    This case report describes the successful treatment of female pattern hair loss (FPHL) with a combination of spironolactone and minoxidil. The patient, a 53-year-old woman, was initially treated with spironolactone 200 mg daily, which resulted in hair regrowth at 12 months but plateaued at 24 months. Twice daily therapy with topical minoxidil 5% solution was then introduced and further regrowth was documented, confirming the additive effect of combination therapy. The authors suggest that combination therapy should be considered for women presenting with FPHL.
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