An Open-Label Randomized Multicenter Study Assessing the Noninferiority of a Caffeine-Based Topical Liquid 0.2% Versus Minoxidil 5% Solution in Male Androgenetic Alopecia

    October 2017 in “ Skin Pharmacology and Physiology
    Rachita Dhurat, Jill Chitallia, Theodor W. May, Ammani M. Jayaraaman, J Madhukara, Subbu Anandan, Pradyumna Vaidya, Adolf Klenk
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    TLDR Caffeine-based liquid 0.2% is as effective as minoxidil 5% for treating male hair loss.
    A study conducted in 2017 aimed to compare the effectiveness of a caffeine-based topical liquid 0.2% to minoxidil 5% solution in treating male androgenetic alopecia. The study involved 210 male participants and found that the caffeine-based topical liquid was noninferior to minoxidil 5% solution in promoting hair growth and reducing hair loss. The caffeine-based topical liquid was also well-tolerated by the participants. The study suggests that caffeine-based topical liquid 0.2% could be a potential alternative treatment for male androgenetic alopecia.
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