Caffeine’s Mechanisms of Action and Its Cosmetic Use

    October 2012 in “ Skin Pharmacology and Physiology
    Andrzej Przemysław Herman, Andrzej Przemysław Herman
    Image of study
    TLDR Caffeine in cosmetics may reduce cellulite, protect skin, and stimulate hair growth, but more research is needed on its use and effects.
    The 2012 document reviews caffeine's role in cosmetics, highlighting its ability to penetrate the skin and its benefits in reducing cellulite, enhancing microcirculation, acting as an antioxidant, and stimulating hair growth. Caffeine prevents fat accumulation and promotes fat degradation by inhibiting phosphodiesterase, which increases cAMP in cells. It protects against UV radiation, potentially preventing UV-induced skin cancers by scavenging radicals and inducing apoptosis in damaged cells. Studies cited include one with a 7% caffeine solution reducing cellulite and another testing a 3% caffeine gel for eye puffiness, though without significant results. Caffeine also inhibits 5-a-reductase, which may help manage androgenetic alopecia, and can remain in hair follicles for up to 48 hours post-shampoo application. The document suggests caffeine's cosmetic potential is significant but calls for further research on dosing, delivery systems, and potential side effects.
    Discuss this study in the Community →

    Research cited in this study

    3 / 3 results

    Related Community Posts Join

    6 / 440 results

      community abusing caffeine boosts DHT levels!

      in Research/Science  1 upvotes 2 months ago
      Caffeine intake may increase DHT levels, but its impact on hair loss is minimal compared to genetic factors. Excessive caffeine can cause health issues, and its effects on hair loss are not directly applicable to humans based on rat studies.

      community Connection between caffeine and hair loss?

      in Product 3 months ago
      Caffeine might raise stress hormones, potentially worsening hair loss. Telogen effluvium is often misattributed to minor stressors rather than significant life events.

      community Caffeine + Dimethylglycine (DMG) Shampoo research

      in Research/Science  6 upvotes 4 months ago
      A user discusses the potential of caffeine and DMG in shampoo for treating hair loss, citing a pending patent and personal plans to test it. They find it more convenient than using minoxidil, tretinoin, and microneedling.

      community Caffeine affects on oral minoxidil

      in Chat  3 upvotes 8 months ago
      Caffeine may interfere with oral minoxidil because caffeine increases blood pressure while minoxidil lowers it. Users discuss potential interactions and effects on hair loss treatment.

      community Caffeine & Alopecia: What the Science Seems to Say

      in Research/Science  17 upvotes 1 year ago
      The conversation discusses the potential benefits of topical caffeine for Androgenetic Alopecia (APA) and female pattern hair loss. While some studies suggest positive results, there's no reliable scientific evidence to strongly recommend caffeine compounds for hair regrowth.

    Similar Research

    5 / 564 results