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    Glossary Phosphodiesterase

    enzyme that breaks down cyclic nucleotides in cells

    Phosphodiesterase (PDE) is an enzyme that plays a crucial role in cellular signaling by breaking down cyclic nucleotides like cAMP and cGMP, which are molecules that transmit signals inside cells. By regulating the levels of these cyclic nucleotides, PDEs help control various physiological processes, including heart rate, inflammation, and even hair growth.

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    Research 10 of 535

    1. The effect of cilostazol, a phosphodiesterase 3 (PDE3) inhibitor, on human hair growth with the dual promoting mechanisms Journal of Dermatological Science · 2018 · 21 citations
    2. Systematic review of newer agents for the management of alopecia areata in adults: Janus kinase inhibitors, biologics and phosphodiesterase‐4 inhibitors 2022 · 12 citations
    3. Efficacy of the phosphodiesterase-4 inhibitor, apremilast, in a patient with severe alopecia areata European Journal of Dermatology · 2019 · 10 citations
    4. Phosphodiesterase inhibitors and prostaglandin analogues in dermatology: A comprehensive review Dermatologic Therapy · 2020 · 9 citations
    5. The use of phosphodiesterase inhibitors for the treatment of alopecia Journal of Dermatological Treatment · 2019 · 3 citations
    6. Comment on ‘Androgenetic alopecia is associated with increased scalp hardness’: role of phosphodiesterase inhibitors? Journal of The European Academy of Dermatology and Venereology · 2020 · 1 citations
    7. The effects of phosphodiesterase 3 (PDE3) inhibitor on hair follicle cell viability and hair growth Seoul National University Open Repository (Seoul National University) · 2020 · 1 citations
    8. 570 Targeting phosphodiesterase 8A (PDE8A) to boost adipogenesis and hair regeneration Journal of Investigative Dermatology · 2024
    9. 467 Novel selective phosphodiesterase inhibitors promote the adipogenic function of dermal fibroblasts: Implication to treat hair loss Journal of Investigative Dermatology · 2021
    10. PD59-09 PHOSPHODIESTERASE INHIBITORS COULD REVERSE THE PROLIFERATION OF BPH EPITHELIAL CELLS INDUCED BY CD8+ T CELLS IN LOW ANDROGEN CONDITION The Journal of Urology · 2018
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