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GlossaryPDE5 inhibitors

block enzyme to improve blood flow in certain conditions

PDE5 inhibitors, or phosphodiesterase type 5 inhibitors, are a class of medications that block the enzyme PDE5, which is involved in regulating blood flow in the body. By inhibiting this enzyme, these drugs help to relax blood vessels and improve blood flow, making them effective treatments for conditions like erectile dysfunction and pulmonary arterial hypertension.

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research Most Recent Findings of Curative Drugs for Lower Urinary Tract Symptoms in Clinical Practice

January 2019 in “Nihon Yakuri Gakkai nenkai yoshishu”

Current treatments for lower urinary tract symptoms include α1-blockers, 5ARIs, PDE5 inhibitors, anticholinergic agents, and β3-adrenergic receptor agonists.

research The Long Term Effects of Doxazosin, Finasteride, and the Combination on Sexual Function in Men Participating in the MTOPS Study

8 citations , April 2004 in “The Journal of Urology”

Doxazosin and finasteride negatively affect sexual function in men with BPH.

research Impact of Hormones on Female Sexual Function and Dysfunction

3 citations , January 2011 in “Female pelvic medicine & reconstructive surgery”

Hormones significantly affect women's sexual function, and more research is needed to improve treatments for sexual dysfunction with minimal side effects.

Novel Penile Ultrasound Technique to Explain Mechanism of Erectile Dysfunction in Young Patients Using Finasteride for Androgenic Alopecia

research Novel Penile Ultrasound Technique to Explain Mechanism of Erectile Dysfunction in Young Patients Using Finasteride for Androgenic Alopecia

1 citations , February 2018 in “The Journal of Sexual Medicine”

Ultrasound shows 96% of young men with erectile dysfunction after using finasteride have abnormal penile tissue.

research Sexual Medicine Reviews: The Premier Review Journal for the Field of Sexual Medicine

1 citations , January 2015 in “Sexual Medicine Reviews”

Current treatments for recurrent ischemic priapism are not well-defined and need more research.

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community Finasteride update/information on Penis/Penile Tissue

in Finasteride/Dutasteride 8 upvotes 3 years ago

Finasteride can reduce DHT in the genitalia, potentially causing side effects like reduced erections and penile fibrosis. Using PDE5 inhibitors like Tadalafil or Sildenafil may help maintain penile health and prevent fibrosis.

community Just started ru58841, ask me anything.

in Research/Science 14 upvotes 2 days ago

The conversation discusses a hair loss treatment regimen including oral dutasteride, oral minoxidil, tadalafil, and the recent addition of RU58841. The user shares experiences with these treatments, noting significant hair regrowth and stabilization, and discusses the cost and preparation of RU58841.

community Hair Loss Treatment Iceberg Chart

in Satire 1376 upvotes 4 years ago

Hair loss treatments discussed include Minoxidil, Finasteride, RU58841, ass hair transplant, topical Viagra, castration, and transitioning to female. A user mentions an experimental drug called M4U-5 (Mousteride) that turns you into a mouse.

community 5mg cialis daily to deal with dutasteride

in Finasteride/Dutasteride 71 upvotes 3 weeks ago

Cialis is used to manage erectile dysfunction caused by finasteride and dutasteride, with mixed results. Some users report improvement, while others consider stopping the medication due to side effects.

community Update July 2025] Most Promising Hair Loss Treatments in Clinical Trials

in Research/Science 269 upvotes 6 months ago

Promising hair loss treatments in clinical trials include Pyrilutamide, GT20029, CB-03-01, and PP405, with potential market releases between 2027 and 2029. Hair cloning remains experimental and expensive, while existing treatments like finasteride, minoxidil, and microneedling continue to be used.

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