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GlossaryPDE5 inhibitors

block enzyme to improve blood flow in certain conditions

PDE5 inhibitors, or phosphodiesterase type 5 inhibitors, are a class of medications that block the enzyme PDE5, which is involved in regulating blood flow in the body. By inhibiting this enzyme, these drugs help to relax blood vessels and improve blood flow, making them effective treatments for conditions like erectile dysfunction and pulmonary arterial hypertension.

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research The Princeton III Consensus Recommendations for the Management of Erectile Dysfunction and Cardiovascular Disease

January 2013 in “Yearbook of Urology”

The Princeton III Consensus recommends assessing cardiovascular risk in men with erectile dysfunction and prioritizing heart health before treating ED, especially in those with potential heart disease.

Novel Penile Ultrasound Technique to Explain Mechanism of Erectile Dysfunction in Young Patients Using Finasteride for Androgenic Alopecia

research Novel Penile Ultrasound Technique to Explain Mechanism of Erectile Dysfunction in Young Patients Using Finasteride for Androgenic Alopecia

1 citations , February 2018 in “The Journal of Sexual Medicine”

Ultrasound shows 96% of young men with erectile dysfunction after using finasteride have abnormal penile tissue.

research Evaluation of Risk of SSRI-Associated Impotence and Low Libido in Men Exposed to Finasteride

April 2016 in “Journal of The American Academy of Dermatology”

Finasteride and SSRIs together increase impotence and low libido risk in men.

research Investigation, Treatment, and Monitoring of Late-Onset Hypogonadism in Males: ISA, ISSAM, and EAU Recommendations

280 citations , May 2005 in “Andrology”

Testosterone treatment for older men can have short-term benefits, but long-term risks are unclear, requiring careful evaluation and monitoring.

research Medical Management of Benign Prostatic Hyperplasia

March 2024 in “Cleveland Clinic journal of medicine”

Alpha-blockers and 5-alpha reductase inhibitors are main treatments for BPH, with new support for phosphodiesterase-5 inhibitors and beta-3 agonists.

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community Finasteride update/information on Penis/Penile Tissue

in Finasteride/Dutasteride 8 upvotes 3 years ago

Finasteride can reduce DHT in the genitalia, potentially causing side effects like reduced erections and penile fibrosis. Using PDE5 inhibitors like Tadalafil or Sildenafil may help maintain penile health and prevent fibrosis.

community Hair Loss Treatment Iceberg Chart

in Satire 1377 upvotes 4 years ago

Hair loss treatments discussed include Minoxidil, Finasteride, RU58841, ass hair transplant, topical Viagra, castration, and transitioning to female. A user mentions an experimental drug called M4U-5 (Mousteride) that turns you into a mouse.

community Just started ru58841, ask me anything.

in Research/Science 14 upvotes 2 months ago

The conversation discusses a hair loss treatment regimen including oral dutasteride, oral minoxidil, tadalafil, and the recent addition of RU58841. The user shares experiences with these treatments, noting significant hair regrowth and stabilization, and discusses the cost and preparation of RU58841.

community Update July 2025] Most Promising Hair Loss Treatments in Clinical Trials

in Research/Science 268 upvotes 8 months ago

Promising hair loss treatments in clinical trials include Pyrilutamide, GT20029, CB-03-01, and PP405, with potential market releases between 2027 and 2029. Hair cloning remains experimental and expensive, while existing treatments like finasteride, minoxidil, and microneedling continue to be used.

community 5mg cialis daily to deal with dutasteride

in Finasteride/Dutasteride 71 upvotes 2 months ago

Cialis is used to manage erectile dysfunction caused by finasteride and dutasteride, with mixed results. Some users report improvement, while others consider stopping the medication due to side effects.

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