research The PDE4 inhibitor, apremilast, suppresses experimentally induced alopecia areata in human skin in vivo
Apremilast may help treat hair loss in alopecia areata.
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research A randomized placebo-controlled single-center pilot study of the safety and efficacy of apremilast in subjects with moderate-to-severe alopecia areata
Apremilast was not effective in treating moderate-to-severe alopecia areata.
research Apremilast treatment of atopic dermatitis and other chronic eczematous dermatoses
This study observed that apremilast treatment improved skin lesions and reduced pruritus in patients with chronic, severe atopic dermatitis and one case of hand and foot dermatitis.
research Lack of efficacy of apremilast in 9 patients with severe alopecia areata
This article hypothesizes that apremilast, a phosphodiesterase 4 inhibitor, could be a targeted treatment for alopecia areata due to its ability to suppress interferon-gamma production, but reports no new clinical results.
research Long-term treatment with apremilast in hidradenitis suppurativa: A 2-year follow-up of initial responders
This study suggests that apremilast shows prolonged efficacy for up to 2 years in hidradenitis suppurativa patients who initially responded to the treatment, although further verification in a larger cohort is needed.
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1 / 1000+ resultscommunity Hair Loss “Cure” for Inflammation: Topical Roflumilast
Topical roflumilast is effective for reducing inflammation in various scalp conditions like seborrheic dermatitis, psoriasis, and eczema, but not proven to stop scarring alopecia. Alternatives like apremilast and Vtama are also discussed for their anti-inflammatory benefits.
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