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    Glossary Apremilast

    medication for inflammatory conditions, inhibiting enzyme PDE4 to reduce inflammation

    Apremilast is a medication used to treat certain inflammatory conditions like psoriasis and psoriatic arthritis. It works by inhibiting an enzyme called phosphodiesterase 4 (PDE4), which helps reduce inflammation in the body.

    Research 10 of 230

    1. The PDE4 inhibitor, apremilast, suppresses experimentally induced alopecia areata in human skin in vivo Journal of Dermatological Science · 2014 · 52 citations
    2. A randomized placebo-controlled single-center pilot study of the safety and efficacy of apremilast in subjects with moderate-to-severe alopecia areata Archives of dermatological research · 2018 · 42 citations
    3. Apremilast treatment of atopic dermatitis and other chronic eczematous dermatoses Journal of the American Academy of Dermatology · 2017 · 31 citations
    4. Lack of efficacy of apremilast in 9 patients with severe alopecia areata Journal of the American Academy of Dermatology · 2017 · 23 citations
    5. Long-term treatment with apremilast in hidradenitis suppurativa: A 2-year follow-up of initial responders Journal of the American Academy of Dermatology · 2020 · 22 citations
    6. Apremilast for extensive and treatment-resistant alopecia areata: a retrospective analysis of five patients European Journal of Dermatology · 2020 · 13 citations
    7. Efficacy of the phosphodiesterase-4 inhibitor, apremilast, in a patient with severe alopecia areata European Journal of Dermatology · 2019 · 10 citations
    8. Apremilast is efficacious in refractory alopecia areata Journal of dermatological treatment · 2019 · 9 citations
    9. Apremilast and tofacitinib exert differential effects in the humanized mouse model of alopecia areata British Journal of Dermatology · 2019 · 5 citations
    10. The relative efficacy of monotherapy with Janus kinase inhibitors, dupilumab and apremilast in adults with alopecia areata: Network meta‐analyses of clinical trials Journal of cosmetic dermatology · 2023 · 2 citations
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    Community 2

    1. Hair Loss “Cure” for Inflammation: Topical Roflumilast Reddit · 14 Jan 2026
    2. The Worst Hair Loss Condition You (MAY) have: LPP Reddit · 31 Aug 2024

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