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    Glossary Apremilast

    medication for inflammatory conditions, inhibiting enzyme PDE4 to reduce inflammation

    Apremilast is a medication used to treat certain inflammatory conditions like psoriasis and psoriatic arthritis. It works by inhibiting an enzyme called phosphodiesterase 4 (PDE4), which helps reduce inflammation in the body.

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    Research 30 of 230

    1. The PDE4 inhibitor, apremilast, suppresses experimentally induced alopecia areata in human skin in vivo Journal of Dermatological Science · 2014 · 52 citations
    2. A randomized placebo-controlled single-center pilot study of the safety and efficacy of apremilast in subjects with moderate-to-severe alopecia areata Archives of dermatological research · 2018 · 42 citations
    3. Apremilast treatment of atopic dermatitis and other chronic eczematous dermatoses Journal of the American Academy of Dermatology · 2017 · 31 citations
    4. Lack of efficacy of apremilast in 9 patients with severe alopecia areata Journal of the American Academy of Dermatology · 2017 · 23 citations
    5. Long-term treatment with apremilast in hidradenitis suppurativa: A 2-year follow-up of initial responders Journal of the American Academy of Dermatology · 2020 · 22 citations
    6. Apremilast for extensive and treatment-resistant alopecia areata: a retrospective analysis of five patients European Journal of Dermatology · 2020 · 13 citations
    7. Efficacy of the phosphodiesterase-4 inhibitor, apremilast, in a patient with severe alopecia areata European Journal of Dermatology · 2019 · 10 citations
    8. Apremilast is efficacious in refractory alopecia areata Journal of dermatological treatment · 2019 · 9 citations
    9. Apremilast and tofacitinib exert differential effects in the humanized mouse model of alopecia areata British Journal of Dermatology · 2019 · 5 citations
    10. The relative efficacy of monotherapy with Janus kinase inhibitors, dupilumab and apremilast in adults with alopecia areata: Network meta‐analyses of clinical trials Journal of cosmetic dermatology · 2023 · 2 citations
    11. Non-FDA-Approved Uses of Apremilast in Dermatology: A Review of Current Available literature Nepal journal of dermatology, venereology & leprology · 2022 · 1 citations
    12. Apremilast for Lichen Planopilaris and Frontal Fibrosing Alopecia: A Case Series Skin · 2017 · 1 citations
    13. Efficacy of Oral Apremilast in The Treatment of Alopecia Areata, at The Tertiary Care Hospital, Karachi Journal of health and rehabilitation research · 2023
    14. Comparing the efficacy of oral apremilast, intralesional corticosteroids, and their combination in patients with patchy alopecia areata: a randomized clinical controlled trial Archives of Dermatological Research · 2024 · 4 citations
    15. Alopecia Areata: an Update on Etiopathogenesis, Diagnosis, and Management Clinical Reviews in Allergy & Immunology · 2021 · 290 citations
    16. Primary cicatricial alopecia Journal of The American Academy of Dermatology · 2016 · 95 citations
    17. Alopecia areata: Animal models illuminate autoimmune pathogenesis and novel immunotherapeutic strategies Autoimmunity reviews · 2016 · 82 citations
    18. The Changing Landscape of Alopecia Areata: The Therapeutic Paradigm Advances in Therapy · 2017 · 77 citations
    19. Cytokine Targeted Therapeutics for Alopecia Areata: Lessons from Atopic Dermatitis and Other Inflammatory Skin Diseases 2017 · 25 citations
    20. Comparative efficacy of oral Janus kinase inhibitors and biologics in adult alopecia areata: A systematic review and Bayesian network meta‐analysis Journal of the European Academy of Dermatology and Venereology · 2024 · 20 citations
    21. Systematic review of newer agents for the management of alopecia areata in adults: Janus kinase inhibitors, biologics and phosphodiesterase‐4 inhibitors 2022 · 12 citations
    22. Phosphodiesterase inhibitors and prostaglandin analogues in dermatology: A comprehensive review Dermatologic Therapy · 2020 · 9 citations
    23. Novel therapies for alopecia areata: The era of rational drug development The Journal of Allergy and Clinical Immunology · 2017 · 9 citations
    24. A narrative review of therapies for scalp dermatomyositis Dermatologic Therapy · 2021 · 7 citations
    25. Frontal fibrosing alopecia: a disease fascinating for the researcher, disappointing for the clinician and distressing for the patient Experimental Dermatology · 2016 · 6 citations
    26. Drugs targeting epithelial–mesenchymal transition molecules for treatment of lichen planopilaris Clinical and experimental dermatology · 2022 · 3 citations
    27. The use of phosphodiesterase inhibitors for the treatment of alopecia Journal of Dermatological Treatment · 2019 · 3 citations
    28. Cytokine-targeted treatment in alopecia areata - new possibilities? Prospects in Pharmaceutical Sciences · 2023 · 1 citations
    29. Comment on ‘Androgenetic alopecia is associated with increased scalp hardness’: role of phosphodiesterase inhibitors? Journal of The European Academy of Dermatology and Venereology · 2020 · 1 citations
    30. Sequential small-molecule therapy for lymphocytic cicatricial alopecia: A multicenter prospective cohort pilot study Journal of the American Academy of Dermatology · 2026