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    Glossary Caffeine

    natural stimulant found in coffee, tea, and energy drinks

    Caffeine, also known as 1,3,7-Trimethylxanthine, is a natural stimulant most commonly found in coffee, tea, and various energy drinks. It works by blocking the action of adenosine, a neurotransmitter that promotes sleep, thereby increasing alertness and reducing the perception of fatigue.

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    1. Caffeine Stimulant used in hair shampoos and lotions
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    Research 10 of 739

    1. The role of hair follicles in the percutaneous absorption of caffeine 2007 · 182 citations
    2. Caffeine’s Mechanisms of Action and Its Cosmetic Use Skin Pharmacology and Physiology · 2012 · 153 citations
    3. Effect of caffeine and testosterone on the proliferation of human hair follicles <i>in vitro</i> International Journal of Dermatology · 2007 · 114 citations
    4. Follicular Penetration of Topically Applied Caffeine via a Shampoo Formulation Skin Pharmacology and Physiology · 2007 · 93 citations
    5. Permeation of topically applied caffeine through human skin – a comparison of <i>in vivo</i> and <i>in vitro</i> data 2009 · 82 citations
    6. Differential effects of caffeine on hair shaft elongation, matrix and outer root sheath keratinocyte proliferation, and transforming growth factor‐β2/insulin‐like growth factor‐1‐mediated regulation of the hair cycle in male and female human hair follicles<i>in vitro</i> British Journal of Dermatology · 2014 · 60 citations
    7. Effects of caffeine and siloxanetriol alginate caffeine, as anticellulite agents, on fatty tissue: histological evaluation Journal of cosmetic dermatology · 2008 · 46 citations
    8. Overview of Caffeine Effects on Human Health and Emerging Delivery Strategies Pharmaceuticals · 2023 · 43 citations
    9. Follicular Penetration of Caffeine from Topically Applied Nanoemulsion Formulations Containing Penetration Enhancers: In vitro Human Skin Studies Skin pharmacology and physiology · 2018 · 35 citations
    10. Development of a Two-Dimensional Model for Predicting Transdermal Permeation with the Follicular Pathway: Demonstration with a Caffeine Study Pharmaceutical research · 2017 · 35 citations
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    Community 10 of 267

    1. Close Up of 1.5 months progress. Minox + 0.5mm Derma Stamp + Caffeine Serum Reddit · 19 May 2026
    2. 3 months topical min 5%, fin 1%, caffeine 1%, biotin 1% and 2 months Dut 2.5 mg, first picture November 20, 2nd picture January 20, happy with the progress Reddit · 23 Jan 2026
    3. Anyone try the 4 in 1 Spray w/ Minoxidil 5%, Caffeine .2%, Melatonin .1%, Tretinoin .01% (81 G)? Reddit · 4 Jan 2026
    4. Charcoal / Ketoconazole / Caffeine shampoo Reddit · 25 Nov 2025
    5. Best scalp serums while on minoxidil and can they contain caffeine? Reddit · 14 Oct 2025
    6. Not bad for just 2 months on RU58841 + minoxidil + caffeine topically. Minoxidil 3mg + 1/2mg Duta orally. Reddit · 3 Oct 2025
    7. Caffeine in hair care – does it really help? Reddit · 26 Sept 2025
    8. If I quit caffeine, will my hair suffer any appreciable effects? Reddit · 9 Aug 2025
    9. 22M with MPB — Want to start minoxidil + finasteride but no topical fin available, any experience with natural DHT blockers like saw palmetto and caffeine? Community · 27 Jul 2025
    10. does caffeine really work as advertised? Reddit · 5 Jul 2025
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