Differential Effects of Caffeine on Hair Shaft Elongation, Matrix and Outer Root Sheath Keratinocyte Proliferation, and Transforming Growth Factor-β2/Insulin-Like Growth Factor-1-Mediated Regulation of the Hair Cycle in Male and Female Human Hair Follicles In Vitro

May 2014 in “ British Journal of Dermatology ”

Fischer Tw, Erika Herczeg-Lisztes, Wolfang Funk, Detlef Zillikens, Tamás Bı́ró, Ralf Paus

caffeine hair shaft elongation keratinocyte proliferation transforming growth factor‐β2 insulin‐like growth factor‐1 hair cycle male hair follicles female hair follicles TGF-β2 IGF-1

Studysummary This study found that caffeine enhanced hair growth and keratinocyte proliferation in human hair follicles, with female follicles showing greater sensitivity than male ones. Our plain-language summary of this paper — not a Tressless recommendation.

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