Growth Hormone Operates as a Neuroendocrine Regulator of Human Hair Growth Ex Vivo

    January 2019 in “ ˜The œjournal of investigative dermatology/Journal of investigative dermatology ”
    Majid Alam, D. Below, Jérémy Chéret … Ralf Paus
    Studysummary This review discusses how neuroendocrine regulation affects human hair follicles and suggests potential therapeutic targets, but it reports no new clinical results.
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    Research cited in this study 13

    1. Olfactory Receptor OR2AT4 Regulates Human Hair Growth Nature Communications · 2018
    2. Identifying Novel Strategies for Treating Human Hair Loss Disorders: Cyclosporine A Suppresses the Wnt Inhibitor, SFRP1, in the Dermal Papilla of Human Scalp Hair Follicles PLOS Biology · 2018
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    4. Human Hair Follicle Organ Culture: Theory, Application, and Perspectives Experimental Dermatology · 2015
    5. Neuroendocrinology of the Hair Follicle: Principles and Clinical Perspectives Trends in Molecular Medicine · 2014
    6. Differential Effects of Caffeine on Hair Shaft Elongation, Matrix and Outer Root Sheath Keratinocyte Proliferation, and Transforming Growth Factor-β2/Insulin-Like Growth Factor-1-Mediated Regulation of the Hair Cycle in Male and Female Human Hair Follicles In Vitro British Journal of Dermatology · 2014
    7. Hypothalamic–Pituitary–Thyroid Axis Hormones Stimulate Mitochondrial Function and Biogenesis in Human Hair Follicles Journal of Investigative Dermatology · 2013
    8. Is Thyrotropin-Releasing Hormone a Novel Neuroendocrine Modulator of Keratin Expression in Human Skin? British Journal of Dermatology · 2013
    9. Thyrotropin Releasing Hormone: A New Player in Human Hair Growth Control ˜The œFASEB journal · 2009
    10. Methods in Hair Research: How to Objectively Distinguish Between Anagen and Catagen in Human Hair Follicle Organ Culture Experimental Dermatology · 2009
    11. The Hair Follicle as a Dynamic Mini-Organ Current Biology · 2009
    12. Human Scalp Hair Follicles Are Both a Target and a Source of Prolactin, Which Serves as an Autocrine and/or Paracrine Promoter of Apoptosis-Driven Hair Follicle Regression American Journal of Pathology · 2006
    13. The Biology of Hair Follicles The New England Journal of Medicine · 1999