Human Hair Follicles Operate a Functional Peripheral Equivalent of the Hypothalamic-Pituitary-Somatotropic Axis Ex Vivo

    December 2022 in “ ˜The œjournal of investigative dermatology/Journal of investigative dermatology ”
    Elijah J. Horesh, Jennifer Gherardini, Majid Alam … Ralf Paus
    Studysummary This article discusses the role of human scalp hair follicles in neurohormone production and their model potential for studying neuroendocrine signaling, reporting no experimental results.
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    Research cited in this study 15

    1. Growth Hormone and the Human Hair Follicle International journal of molecular sciences · 2021
    2. Resident Human Dermal Gamma Delta T-Cells Operate as Stress Sentinels: Lessons from the Hair Follicle Journal of Autoimmunity · 2021
    3. Hair Follicle Chemosensation: TRPM5 Signaling Is Required for Anagen Maintenance Journal of Investigative Dermatology · 2021
    4. Dermal Adipose Tissue Secretes HGF to Promote Human Hair Growth and Pigmentation Journal of Investigative Dermatology · 2021
    5. Hair Follicle Immune Privilege and Its Collapse in Alopecia Areata Experimental dermatology · 2020
    6. Deciphering the Molecular Morphology of the Human Hair Cycle: Wnt Signalling During the Telogen–Anagen Transformation British Journal of Dermatology · 2019
    7. Growth Hormone Operates as a Neuroendocrine Regulator of Human Hair Growth Ex Vivo ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2019
    8. Olfactory Receptor OR2AT4 Regulates Human Hair Growth Nature Communications · 2018
    9. Identifying Novel Strategies for Treating Human Hair Loss Disorders: Cyclosporine A Suppresses the Wnt Inhibitor, SFRP1, in the Dermal Papilla of Human Scalp Hair Follicles PLOS Biology · 2018
    10. Exploring the Brain-Skin Connection: Leads and Lessons from the Hair Follicle Current research in translational medicine · 2016
    11. Vasoactive Intestinal Peptide, Whose Receptor-Mediated Signaling May Be Defective in Alopecia Areata, Provides Protection from Hair Follicle Immune Privilege Collapse British journal of dermatology/British journal of dermatology, Supplement · 2016
    12. Human Hair Follicle Organ Culture: Theory, Application, and Perspectives Experimental Dermatology · 2015
    13. Neuroendocrinology of the Hair Follicle: Principles and Clinical Perspectives Trends in Molecular Medicine · 2014
    14. Somatostatin Expression in Human Hair Follicles and Its Potential Role in Immune Privilege ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2013
    15. Scalp Hair Loss After Transsphenoidal Adenomectomy in Patients With Acromegaly Clinical Endocrinology · 2012