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GlossarySomatostatin

peptide hormone that inhibits growth hormone and insulin release

Somatostatin, also known as Growth Hormone-Inhibiting Hormone (GHIH), is a peptide hormone that regulates the endocrine system by inhibiting the release of several other hormones, including growth hormone and insulin. It is produced in various tissues throughout the body, including the hypothalamus, pancreas, and gastrointestinal tract, and plays a crucial role in maintaining hormonal balance and digestive processes.

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research A Subpopulation of Itch-Sensing Neurons Marked by Ret and Somatostatin Expression

70 citations, February 2016 in “EMBO reports”

Scientists found a specific group of itch-sensing nerve cells in mice important for feeling itch but not for sensing heat or touch.

research Estrogen-Dependent Development of Sex Differences in Somatostatin Neurons of the Hypothalamic Periventricular Nucleus

19 citations, March 1998 in “Endocrinology”

Male rats have more somatostatin neurons than females due to testosterone converting to estrogen during early development.

Recent Advances in Neuropeptide-Related Omics and Gene Editing: Spotlight on NPY and Somatostatin and Their Roles in Growth and Food Intake of Fish

research Recent Advances in Neuropeptide-Related Omics and Gene Editing: Spotlight on NPY and Somatostatin and Their Roles in Growth and Food Intake of Fish

October 2022 in “Frontiers in Endocrinology”

New tools show that in fish, NPY increases feeding and somatostatin decreases it.

Medications Affecting the Insulin-Like Growth Factor 1/Growth Hormone Axis, Including Teprotumumab, Somatostatin Analogs, and Anti-Calcitonin Gene-Related Peptide Monoclonal Antibodies, Are Associated With Elevated Reporting Odds of Alopecia in Women: A Pharmacovigilance Study

research Medications Affecting the Insulin-Like Growth Factor 1/Growth Hormone Axis, Including Teprotumumab, Somatostatin Analogs, and Anti-Calcitonin Gene-Related Peptide Monoclonal Antibodies, Are Associated With Elevated Reporting Odds of Alopecia in Women: A Pharmacovigilance Study

April 2023 in “Journal of The American Academy of Dermatology”

Some drugs linked to growth hormones may increase the chance of hair loss in women.

research An Integrative View of Mammalian Seasonal Neuroendocrinology

85 citations, May 2019 in “Journal of neuroendocrinology”

The article concludes that better understanding gene regulation related to seasonal changes can offer insights into the mechanisms of seasonal timing in mammals.

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