Scalp Hair Loss After Transsphenoidal Adenomectomy in Patients With Acromegaly

September 2012 in “ Clinical Endocrinology ”

Shozo Yamada, Noriaki Fukuhara, Hiroshi Nishioka, Mitsuo Yamaguchi-Okada, Akira Takeshita, Yasuhiro Takeuchi

scalp hair loss transsphenoidal adenomectomy acromegaly growth hormone deficiency

TLDR More than half of patients who had acromegaly surgery experienced hair loss, with varying degrees of recovery.

In a study from 2013 involving 484 patients who had undergone surgery for acromegaly, 54% (263 patients) reported hair loss within 3 to 6 months post-operation. Hair loss severity was minimal in 10% (50 patients), moderate in 24% (117 patients), and severe in 20% (96 patients). The condition was more prevalent in females, those cured of acromegaly, and those with severe postoperative growth hormone deficiency. Of those who experienced hair loss, 32% (85 patients) had full recovery, 34% (88 patients) had incomplete recovery, and 34% (90 patients) had little to no recovery, with recovery being less common in males and those with severe hair loss. The study is significant as it is the first large-scale, single-centre clinical study to address this issue and suggests that patients should be informed about the potential for hair loss after acromegaly surgery.

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Research cited in this study

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research Hormones and Hair Growth

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Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

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community Dutasteride is better than Finasteride. Scalp Testosterone increase WON'T accelerate your hair loss...

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Dutasteride potentially being more effective than Finasteride in treating hair loss due to its ability to suppress DHT levels more significantly. Dutasteride also has fewer sexual side effects compared to Finasteride.

community What do these pictures say about my hair and scalp if anything? Miniaturization, inflammation, etc.?

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Hair loss and scalp issues, with people discussing possible treatments such as Nizoral shampoo, Minoxidil, neem oil, and finasteride.

community Estrogen is an anabolic for scalp hair, if you mix it with growth stimulants such as oral minoxidil. All we need is an artificial SARM-estrogen that will work only with hair and will be invisible for the rest of the body + some next level AA only for hair – goodbye hair transplant industry

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The post discusses potential links between low vitamin D levels and hair loss, and how correcting this might impact the effectiveness of Minoxidil and Finasteride treatments. The responses vary, with some suggesting that vitamin D deficiency would cause overall scalp hair loss, while others believe it would first affect the most sensitive areas.

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research Scalp Hair Loss After Transsphenoidal Adenomectomy in Patients With Acromegaly

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More than half of patients who had acromegaly surgery experienced hair loss, with varying degrees of recovery.