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    Glossary Acromegaly

    hormonal disorder causing abnormal growth of bones and tissues

    Acromegaly is a hormonal disorder that results from the excessive production of growth hormone (GH) by the pituitary gland, often due to a benign tumor called an adenoma. This condition leads to the enlargement of bones and tissues, particularly in the hands, feet, and face, and can cause various complications if left untreated.

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      research Female Gonadal Function before and after Treatment of Acromegaly

      74 citations , July 2010 in “The Journal of Clinical Endocrinology & Metabolism”
      This study found that gonadal dysfunction is very common in premenopausal women with acromegaly and may be caused by hyperprolactinemia, GH/IGF-I excess, or tumor effects.

      research Menstrual Irregularity in Women with Acromegaly

      66 citations , August 1999 in “The Journal of Clinical Endocrinology & Metabolism”
      This study found that menstrual irregularity is common in women with acromegaly, with high GH levels, estrogen deficiency, and larger tumors correlating with more severe irregularity.

      research Some Clues and Pitfalls in the Diagnosis of Acromegaly

      7 citations , July 2004 in “Endocrine practice”
      This case report highlights how persistent hyperphosphatemia, albeit often overlooked, can precede clinical acromegaly symptoms in women, complicating diagnosis due to overlapping features with oral contraceptive use and polycystic ovary syndrome.