Severe Scalp Hair Loss in a Female Patient with Acromegaly Treated with Lanreotide Autogel After Unsuccessful Surgery

    October 2015 in “ Clinical Case Reports ”
    Cristina Álvarez-Escolá, Jersy Cárdenas-Salas, Beatriz Pelegrina, Angel Sanz‐Valtierra, Beatriz Lecumberri
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    TLDR A woman with acromegaly experienced severe hair loss from a drug called Lanreotide Autogel, which improved after stopping the treatment.
    The document described a 49-year-old female patient with acromegaly who suffered severe nonscarring diffuse scalp hair loss after being treated with Lanreotide Autogel (LA) following an unsuccessful surgery. The hair loss began after the second dose of LA and was severe enough to warrant discontinuation of the treatment due to the patient's psychological distress. The patient's hair condition improved significantly within 5 months after stopping LA. This case highlighted scalp hair loss as a potential side effect of somatostatin analogs therapy, which may be associated with a rapid decrease in GH/IGF-1 levels, though a direct effect of the drug itself could not be ruled out. The document called for more research to assess hair loss as an indicator of treatment efficacy and its effects on patients' quality of life.
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