Efficacy and Safety of Oral Minoxidil 5 mg Once Daily in the Treatment of Male Patients with Androgenetic Alopecia: An Open-Label and Global Photographic Assessment

    September 2020 in “ Dermatology and therapy ”
    Ratchathorn Panchaprateep, Suparuj Lueangarun
    Studysummary This study found that low-dose oral minoxidil 5 mg daily significantly increased hair growth in men with androgenetic alopecia over 24 weeks, with increased hair count and vertex area improvement, though most experienced hypertrichosis and some had pedal edema.
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    Research cited in this study 24

    1. How Safe Is Prescribing Oral Minoxidil in Patients Allergic to Topical Minoxidil? Journal of The American Academy of Dermatology · 2020
    2. Effectiveness and Safety of Low-Dose Oral Minoxidil in Male Androgenetic Alopecia Journal of The American Academy of Dermatology · 2019
    3. The Efficacy and Safety of Dutasteride Compared with Finasteride in Treating Men with Androgenetic Alopecia: A Systematic Review and Meta-Analysis Clinical Interventions in Aging · 2019
    4. Evaluation of Long-Term Efficacy of Finasteride in Korean Men with Androgenetic Alopecia Using the Basic and Specific Classification System Journal of Dermatology · 2018
    5. Androgenetic Alopecia Treatment in Asian Men PubMed · 2018
    6. Female Pattern Hair Loss: A Pilot Study Investigating Combination Therapy with Low-Dose Oral Minoxidil and Spironolactone International Journal of Dermatology · 2017
    7. Age-Related Hair Changes in Men: Mechanisms and Management of Alopecia and Graying Maturitas · 2014
    8. Promotive Effect of Topical Ketoconazole, Minoxidil, and Minoxidil with Tretinoin on Hair Growth in Male Mice ISRN Pharmacology (Print) · 2014
    9. Microarray Analysis of Androgenetic and Senescent Alopecia: Comparison of Gene Expression Shows Two Distinct Profiles Journal of Dermatological Science · 2013
    10. Long-Pulsed Nd:YAG Laser in the Treatment of Facial Hypertrichosis During Topical Minoxidil Therapy Journal of cosmetic and laser therapy · 2013
    11. Minoxidil: Mechanisms of Action on Hair Growth British Journal of Dermatology · 2004
    12. Hypertrichosis in Females Applying Minoxidil Topical Solution and in Normal Controls Journal of The European Academy of Dermatology and Venereology · 2003
    13. Finasteride in the Treatment of Men with Frontal Male Pattern Hair Loss Journal of The American Academy of Dermatology · 1999
    14. Diffuse Hypertrichosis During Treatment with 5% Topical Minoxidil British Journal of Dermatology · 1997
    15. Diffuse Hypertrichosis During Treatment with 5% Topical Minoxidil British Journal of Dermatology · 1997
    16. The Effect of Topical Minoxidil on Hair Follicular Cycles of Rats Journal of Dermatology · 1990
    17. Telogen Effluvium and Minoxidil Journal of The American Academy of Dermatology · 1989
    18. Scalp Comedones After Topical Minoxidil Journal of The American Academy of Dermatology · 1985
    19. Minoxidil in Patients with Chronic Left Heart Failure: Contrasting Hemodynamic and Clinical Effects in a Controlled Trial Circulation · 1984
    20. Minoxidil Stimulates Cutaneous Blood Flow in Human Balding Scalps: Pharmacodynamics Measured by Laser Doppler Velocimetry and Photopulse Plethysmography Journal of Investigative Dermatology · 1984
    21. Minoxidil Annals of Internal Medicine · 1981
    22. Pharmacology and Pharmacokinetics of Minoxidil Journal of Cardiovascular Pharmacology · 1980
    23. Minoxidil Therapy in Refractory Hypertension: Analysis of 155 Patients Nephron · 1978
    24. Minoxidil for Severe Hypertension After Failure of Other Hypotensive Drugs BMJ · 1977

    Related research 9

    1. Randomized Trial of Microneedling Combined With 2% Minoxidil Topical Solution for the Treatment of Female Pattern Hair Loss in a Chinese Population Journal of Cosmetic Dermatology · 2022
    2. Sisaipho Alopecia Areata Treated With Tofacitinib and Oral Minoxidil JAAD case reports · 2022
    3. Bicalutamide Improves Minoxidil-Induced Hypertrichosis in Female Pattern Hair Loss: A Retrospective Review of 35 Patients Journal of The American Academy of Dermatology · 2021
    4. Role of Low Dose Oral Minoxidil in the Treatment of Hair Loss: A Review Cosmoderma · 2021
    5. Efficacy and Safety of Oral Minoxidil 5 mg Once Daily in the Treatment of Male Patients with Androgenetic Alopecia: An Open-Label and Global Photographic Assessment Dermatology and therapy · 2020
    6. Minoxidil And Its Use In Hair Disorders: A Review Drug Design Development and Therapy · 2019
    7. Generalized Hypertrichosis After Treatment With Topical Minoxidil Clinical and Experimental Dermatology · 1994
    8. The Belgian Ten-Center Open Label Trial of Topical 2% Minoxidil Solution in Early Male Pattern Alopecia International Journal of Dermatology · 1988
    9. Topical Minoxidil for Hair Growth in Alopecia Areata and Androgenetica Drugs · 1987