Randomized Trial of Microneedling Combined With 2% Minoxidil Topical Solution for the Treatment of Female Pattern Hair Loss in a Chinese Population

October 2022 in “ Journal of Cosmetic Dermatology ”

Yao Zhang, Youyu Sheng, Yibin Zeng, Ruiming Hu, Jun Zhao, Wuqing Wang, Qinping Yang

microneedling 2% minoxidil female pattern hair loss Sinclair scale hair counts adverse reactions MN minoxidil FPHL

TLDR Combining microneedling with 2% minoxidil is more effective and safe for treating female pattern hair loss than using minoxidil alone.

This randomized, controlled trial involving 40 Chinese women aged 18-50 evaluated the efficacy of combining microneedling (MN) with 2% minoxidil for treating female pattern hair loss (FPHL). Over 24 weeks, the group receiving both treatments showed significantly higher clinical efficacy (85% vs. 45%), greater reduction in the Sinclair scale, and increased hair counts compared to the minoxidil-only group. Mild adverse reactions were reported, but no serious side effects occurred. The study concluded that MN combined with minoxidil is a more effective and safe treatment for FPHL than minoxidil alone.

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