The Efficacy and Safety of Dutasteride Compared with Finasteride in Treating Men with Androgenetic Alopecia: A Systematic Review and Meta-Analysis

    February 2019 in “ Clinical Interventions in Aging ”
    Zhongbao Zhou, Shiqiang Song, Zhenli Gao … Yuanshan Cui
    Studysummary This meta-analysis found that dutasteride was more effective than finasteride in increasing hair count and improving photographic assessments for men with androgenetic alopecia, while both drugs had similar rates of sexual dysfunction-related adverse effects.
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    Research cited in this study 21

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    2. Negative Impact of Testosterone Deficiency and 5α-Reductase Inhibitors Therapy on Metabolic and Sexual Function in Men Advances in Experimental Medicine and Biology · 2017
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    6. A Randomized, Active- and Placebo-Controlled Study of the Efficacy and Safety of Different Doses of Dutasteride Versus Placebo and Finasteride in the Treatment of Male Subjects with Androgenetic Alopecia Journal of The American Academy of Dermatology · 2014
    7. Quality of Life Assessment in Male Patients with Androgenetic Alopecia: Results of a Prospective, Multicenter Study Annals of Dermatology · 2012
    8. Evaluation of Efficacy and Safety of Finasteride 1 mg in 3177 Japanese Men with Androgenetic Alopecia Journal of Dermatology · 2011
    9. Molecular Basis of Androgenetic Alopecia: From Androgen to Paracrine Mediators Through Dermal Papilla Journal of Dermatological Science · 2010
    10. The Ludwig Pattern of Androgenetic Alopecia Is Due to a Hierarchy of Androgen Sensitivity Within Follicular Units That Leads to Selective Miniaturization and a Reduction in the Number of Terminal Hairs Per Follicular Unit British Journal of Dermatology · 2008
    11. Association of Androgenetic Alopecia With Smoking and Its Prevalence Among Asian Men Archives of Dermatology · 2007
    12. The Importance of Dual 5α-Reductase Inhibition in the Treatment of Male Pattern Hair Loss: Results of a Randomized Placebo-Controlled Study of Dutasteride Versus Finasteride Journal of The American Academy of Dermatology · 2006
    13. Changes in Hair Weight in Men with Androgenetic Alopecia After Treatment with Finasteride (1 mg Daily): Three- and Four-Year Results Journal of The American Academy of Dermatology · 2006
    14. Marked Suppression of Dihydrotestosterone in Men with Benign Prostatic Hyperplasia by Dutasteride, a Dual 5α-Reductase Inhibitor ˜The œJournal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism · 2004
    15. Long-Term Multinational Experience with Finasteride 1 mg in the Treatment of Men with Androgenetic Alopecia PubMed · 2002
    16. A Community Study of Male Androgenetic Alopecia in Bishan, Singapore PubMed · 2000
    17. Fortnightly Review: Male Pattern Androgenetic Alopecia BMJ · 1998
    18. Male Pattern Hair Loss: Current Understanding International Journal of Dermatology · 1998
    19. The Effect of Finasteride, a 5 Alpha-Reductase Inhibitor, on Scalp Skin Testosterone and Dihydrotestosterone Concentrations in Patients with Male Pattern Baldness The Journal of Clinical Endocrinology and Metabolism · 1994
    20. Psychological Effects of Androgenetic Alopecia on Women: Comparisons with Balding Men and Female Control Subjects Journal of The American Academy of Dermatology · 1993
    21. The Psychological Effects of Androgenetic Alopecia in Men Journal of The American Academy of Dermatology · 1992

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